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Review
. 1987 Sep;28(1):211-4.
doi: 10.1002/ajmg.1320280128.

Decreased superoxide dismutase-2 activity in a patient with ring chromosome 6

K Yoshimitsu  1 , Y Nishi, Y Kobayashi, O Yoshimura, K Ohama, N Oguma, T Usui
Affiliations
Review

Decreased superoxide dismutase-2 activity in a patient with ring chromosome 6

K Yoshimitsu et al. Am J Med Genet. 1987 Sep.

Abstract

Manganese superoxide dismutase (SOD-2) activity was measured in erythrocytes and leukocytes of a patient with ring chromosome 6. Compared to normal control individuals, SOD-2 activity in leukocytes of the patient was lower, whereas cuprozinc SOD (SOD-1) activity was normal. These findings suggest the cause of decreased enzyme activity is the effect of the ring form on production of the enzyme or inherent instability of ring chromosomes.

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