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. 2020 Oct 28;92(4):e20201080.
doi: 10.1590/0001-3765202020201080. eCollection 2020.

Cardiac glycosides and COVID-19: would it be a promising therapeutic approach?

Eftychios Siniorakis  1 , Spyridon Arvanitakis  1 , Maximilianos Elkouris  2
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Cardiac glycosides and COVID-19: would it be a promising therapeutic approach?

Eftychios Siniorakis et al. An Acad Bras Cienc. .
Free article

Abstract

Cardiac glycosides have been found to have an anti-viral effect. This was noted in the past during various epidemics including MERS and SARS. It is due to their inhibitory effect on the Na, K-ATPase membrane pump. Furthermore, they exhibit anti-inflammatory properties. These preclinical observations may prove useful in further clinical utility of these well-known compounds in the current COVID-19 pandemic.

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