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Randomized Controlled Trial
. 2021 Oct;29(5):267-275.
doi: 10.1080/10669817.2020.1834322. Epub 2020 Nov 5.

Pragmatic application of manipulation versus mobilization to the upper segments of the cervical spine plus exercise for treatment of cervicogenic headache: a randomized clinical trial

Addison Lerner-Lentz  1 , Bryan O'Halloran  2 , Megan Donaldson  3 , Joshua A Cleland  4
Affiliations
Randomized Controlled Trial

Pragmatic application of manipulation versus mobilization to the upper segments of the cervical spine plus exercise for treatment of cervicogenic headache: a randomized clinical trial

Addison Lerner-Lentz et al. J Man Manip Ther. 2021 Oct.

Abstract

Background: The effectiveness of manipulation versus mobilization for the management of spinal conditions, including cervicogenic headache, is conflicting. However, a pragmatic approach comparing manipulation to mobilization has not been examined in a patient population with cervicogenic headache.

Objectives: To evaluate the effectiveness of manipulation compared to mobilization applied in a pragmatic fashion for patients with cervicogenic headache.

Methods: Forty-five (26 females) patients with cervicogenic headache (mean age 47.8 ± SD 16.9 years) were randomly assigned to receive either pragmatically selected manipulation or mobilization. Outcomes were measured at baseline, the second visit, discharge, and 1-month follow-up and included the Neck Disability Index (NDI), Numeric Pain Rating Scale (NPRS), the Headache Impact Test (HIT-6), the Global Rating of Change (GRC), the Patient Acceptable Symptoms Scale (PASS). The primary aim (effects of treatment on disability and pain were examined with a mixed-model analysis of variance (ANOVA), with treatment group (manipulation versus mobilization) as the between subjects variable and time (baseline, 48 hours, discharge and follow-up) as the within subjects variable.

Results: The interaction for the mixed model ANOVA was not statistically significant for NDI (p = 0.91), NPRS (p = 0.81), or HIT (p = 0.89). There was no significant difference between groups for the GRC or PASS.

Discussion and conclusion: The results suggest that manipulation has similar effects on disability, pain, GRC, and cervical range of motion as mobilization when applied in a pragmatic fashion for patients with cervicogenic headaches.

Clinicaltrials.gov: NCT03919630.

Keywords: Cervicogenic headache; manipulation; mobilization; pragmatic.

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Conflict of interest statement

Josh Cleland teaches manual therapy courses which often include techniques used in this clinical trial.

Figures

Figure 1.
Figure 1.
Cervical rotation manipulation
Figure 2.
Figure 2.
Longitudinal cephalad C1-C2 manipulation
Figure 3.
Figure 3.
Flow diagram of subject recruitment and retention
Figure 4.
Figure 4.
Neck Disability Index scores (0-50) at each time period for both groups
See this image and copyright information in PMC

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