Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Mar;33(2):191-195.
doi: 10.1038/s41443-020-00360-0. Epub 2020 Nov 5.

Zinner syndrome and infertility─a literature review based on a clinical case

Aybike Hofmann  1 , Franziska Vauth  2 , Wolfgang H Roesch  2
Affiliations
Review

Zinner syndrome and infertility─a literature review based on a clinical case

Aybike Hofmann et al. Int J Impot Res. 2021 Mar.

Erratum in

Abstract

Zinner syndrome (ZS) is a rare congenital malformation associated with seminal vesicle cysts, ejaculatory duct obstruction, and ipsilateral renal agenesis. The main treatment focus so far has been on symptomatic patients. Therefore, surgery has been reserved for these patients, and surgical treatment is mainly aimed at pain relief. ZS seems to be frequently associated with infertility, but diagnosing is challenging, particularly during adolescence. This literature review of ZS and infertility is based on the medical report of one adolescent patient.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Preoperative MRI of the pelvis - demonstrating enlarged seminal vesicle cysts in the retrovesical space on the left-hand side.
See this image and copyright information in PMC

References

    1. Cascini V, Di Renzo D, Guerriero V, Lauriti G, Lelli Chiesa P. Zinner syndrome in pediatric age: issues in the diagnosis and treatment of a rare malformation complex. Front Pediatr. 2019;7:129. doi: 10.3389/fped.2019.00129. - DOI - PMC - PubMed
    1. van den Ouden D, Blom JH, Bangma C, de Spiegeleer AH. Diagnosis and management of seminal vesicle cysts associated with ipsilateral renal agenesis: a pooled analysis of 52 cases. Eur Urol. 1998;33:433–40.. doi: 10.1159/000019632. - DOI - PubMed
    1. Florim S, Oliveira V, Rocha D. Zinner syndrome presenting with intermittent scrotal pain in a young man. Radio Case Rep. 2018;13:1224–7. doi: 10.1016/j.radcr.2018.08.012. - DOI - PMC - PubMed
    1. Pereira BJ, Sousa L, Azinhais P, Conceição P, Borges R, Leão R, et al. Zinner’s syndrome: an up-to-date review of the literature based on a clinical case. Andrologia. 2009;41:322–30.. doi: 10.1111/j.1439-0272.2009.00939.x. - DOI - PubMed
    1. Naval-Baudin P, Carreño García E, Sanchez Marquez A, Valcárcel José J, Romero NM. Multicystic seminal vesicle with ipsilateral renal agenesis: two cases of Zinner syndrome. Scand J Urol. 2017;51:81–4. doi: 10.1080/21681805.2016.1257650. - DOI - PubMed