Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Dec;56(6):675-676.
doi: 10.1007/s11262-020-01805-w. Epub 2020 Nov 5.

Enigmatic PreS deletions in hepatitis B virus DNA

Affiliations
Editorial

Enigmatic PreS deletions in hepatitis B virus DNA

Wolfram H Gerlich et al. Virus Genes. 2020 Dec.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Wang T, Qin Y, Zhang J, Li X, Tong S, Zhao W, Zhang J (2020) An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene. Virus Genes. 10.1007/s11262-020-01787-9 - PubMed
    1. Peiffer KH, Kuhnhenn L, Jiang B, Mondorf A, Vermehren J, Knop V, Susser S, Walter D, Dietz J, Carra G, Finkelmeier F, Zeuzem S, Sarrazin C, Hildt E. Divergent preS sequences in virion-associated hepatitis B virus genomes and subviral HBV surface antigen particles from HBV e antigen-negative patients. J Infect Dis. 2018;218(1):114–123. doi: 10.1093/infdis/jiy119. - DOI - PubMed
    1. Buckwold VE, Xu Z, Chen M, Yen TS, Ou JH. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol. 1996;70(9):5845–5851. doi: 10.1128/JVI.70.9.5845-5851.1996. - DOI - PMC - PubMed
    1. Bruss V. A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation. J Virol. 1997;71(12):9350–9357. doi: 10.1128/JVI.71.12.9350-9357.1997. - DOI - PMC - PubMed
    1. Rabe B, Delaleau M, Bischof A, Foss M, Sominskaya I, Pumpens P, Cazenave C, Castroviejo M, Kann M. Nuclear entry of hepatitis B virus capsids involves disintegration to protein dimers followed by nuclear reassociation to capsids. PLoS Pathog. 2009;5(8):e1000563. doi: 10.1371/journal.ppat.1000563. - DOI - PMC - PubMed

LinkOut - more resources