Purinergic signalling in the cardiovascular system-a tribute to Geoffrey Burnstock
- PMID: 33151503
- PMCID: PMC7954917
- DOI: 10.1007/s11302-020-09734-x
Purinergic signalling in the cardiovascular system-a tribute to Geoffrey Burnstock
Abstract
Geoffrey Burnstock made groundbreaking discoveries on the physiological roles of purinergic receptors and led on P2 purinergic receptor classification. His knowledge, vision and leadership inspired and influenced the international scientific community. I had the privilege of spending over 10 years (from 1985) with Geoff at the Department of Anatomy and Developmental Biology, initially as a PhD student and then as a postdoctoral research fellow. I regarded him with enormous admiration and affection. This review on purinergic signalling in the cardiovascular system is a tribute to Geoff. It includes some personal recollections of Geoff.
Keywords: ATP; Cardiovascular system; Purine receptors.
Conflict of interest statement
Vera Ralevic declares that she has no conflict of interest.
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- Burnstock G. A basis for distinguishing two types of purinergic receptor. In: Straub RW, Bolis L, editors. Cell membrane receptors for drugs and hormones: a multidisciplinary approach. New York: Raven Press; 1978. pp. 107–118.
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- Fredholm BB, Frenguelli BG, Hills R, IJzerman AP, Jacobson KA, Klotz KN, Linden J, Müller CE, Schwabe U, Stiles GL (2019). Adenosine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE 2019(4). Available from: 10.2218/gtopdb/F3/2019.4
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