Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr;184(4):753-754.
doi: 10.1111/bjd.19664. Epub 2021 Jan 4.

Assessment of familial risk in patients with hidradenitis suppurativa

R L Bruinsma  1 , K Fajgenbaum  2 , Y Yang  3 , M Del Mar Melendez-Gonzalez  4 , K L Mohlke  3 , Y Li  3   5   6 , C Sayed  7
Affiliations

Assessment of familial risk in patients with hidradenitis suppurativa

R L Bruinsma et al. Br J Dermatol. 2021 Apr.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: Christopher J. Sayed, MD has the following conflicts of interest to disclose:

Abbvie, Inc: speaker, co-investigator, and advisory board

Novartis: speaker, co-investigator

InflaRx: investigator, scientific advisory board

UCB: investigator

Chemocentryx: investigator

Figures

Figure 1:
Figure 1:
A. Age-adjusted recurrence risk ratios of hidradenitis suppurativa. B. Sibling Relative Recurrence Risk for HS compared to diseases with known genetic contributions–. *λs in psoriasis of 1.6–4.6 was calculated based on a reported estimate 8–23% of first-degree relatives of psoriasis patients being affected and an assumed population prevalence of 5%
See this image and copyright information in PMC

References

    1. Alikhan A, Sayed C, Alavi A, et al. North American Clinical Management Guidelines for Hidradenitis Suppurativa: a Publication from the United States and Canadian Hidradenitis Suppurativa Foundations. Part I: Diagnosis, Evaluation, and the use of Complementary and Procedural Management. Journal of the American Academy of Dermatology. 2019. - PMC - PubMed
    1. Schrader AM, Deckers IE, van der Zee HH, Boer J, Prens EP. Hidradenitis suppurativa: a retrospective study of 846 Dutch patients to identify factors associated with disease severity. Journal of the American Academy of Dermatology. 2014;71(3):460–467. - PubMed
    1. Wray NR, Yang J, Goddard ME, Visscher PM. The genetic interpretation of area under the ROC curve in genomic profiling. PLoS Genet. 2010;6(2):e1000864. - PMC - PubMed
    1. Cordell HJ, Olson JM. Correcting for ascertainment bias of relative-risk estimates obtained using affected-sib-pair linkage data. Genet Epidemiol. 2000;18(4):307–321. - PubMed
    1. van Straalen KR, Prens EP, Willemsen G, Boomsma DI, van der Zee HH. Contribution of Genetics to the Susceptibility to Hidradenitis Suppurativa in a Large, Cross-Sectional Dutch Twin Cohort. JAMA Dermatol. 2020. - PMC - PubMed

Publication types

MeSH terms