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. 2020 Nov 2;18(11):1537-1570.
doi: 10.6004/jnccn.2020.0052.

Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology

Louis Burt Nabors  1 , Jana Portnow  2 , Manmeet Ahluwalia  3 , Joachim Baehring  4 , Henry Brem  5 , Steven Brem  6 , Nicholas Butowski  7 , Jian L Campian  8 , Stephen W Clark  9 , Andrew J Fabiano  10 , Peter Forsyth  11 , Jona Hattangadi-Gluth  12 , Matthias Holdhoff  5 , Craig Horbinski  13 , Larry Junck  14 , Thomas Kaley  15 , Priya Kumthekar  13 , Jay S Loeffler  16 , Maciej M Mrugala  17 , Seema Nagpal  18 , Manjari Pandey  19 , Ian Parney  17 , Katherine Peters  20 , Vinay K Puduvalli  21 , Ian Robins  22 , Jason Rockhill  23 , Chad Rusthoven  24 , Nicole Shonka  25 , Dennis C Shrieve  26 , Lode J Swinnen  5 , Stephanie Weiss  27 , Patrick Yung Wen  28 , Nicole E Willmarth  29 , Mary Anne Bergman  30 , Susan D Darlow  30
Affiliations

Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology

Louis Burt Nabors et al. J Natl Compr Canc Netw. .

Abstract

The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas to metastatic brain disease. The involvement of an interdisciplinary team, including neurosurgeons, radiation therapists, oncologists, neurologists, and neuroradiologists, is a key factor in the appropriate management of CNS cancers. Integrated histopathologic and molecular characterization of brain tumors such as gliomas should be standard practice. This article describes NCCN Guidelines recommendations for WHO grade I, II, III, and IV gliomas. Treatment of brain metastases, the most common intracranial tumors in adults, is also described.

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