Structure and function of E. coli promoter DNA
- PMID: 3315462
- DOI: 10.3109/10409238709101483
Structure and function of E. coli promoter DNA
Abstract
The process of transcription initiation requires both the recognition of a promoter site by RNA polymerase and the melting of a short stretch of DNA. In this review I discuss the properties of promoters that are relevant to sequence recognition and to the ability of the polymerase to act as a melting protein. The regulation of promoter activity is thus dependent on both factors interacting with RNA polymerase and so altering its affinity for promoter sites and also modulations of DNA structure.
Similar articles
-
Domain 1.1 of the sigma(70) subunit of Escherichia coli RNA polymerase modulates the formation of stable polymerase/promoter complexes.J Mol Biol. 2001 Jun 8;309(3):561-72. doi: 10.1006/jmbi.2001.4690. J Mol Biol. 2001. PMID: 11397080
-
Investigations of Escherichia coli promoter sequences with artificial neural networks: new signals discovered upstream of the transcriptional startpoint.Proc Int Conf Intell Syst Mol Biol. 1995;3:292-9. Proc Int Conf Intell Syst Mol Biol. 1995. PMID: 7584449
-
Sequence determinants for the recognition of the fork junction DNA containing the -10 region of promoter DNA by E. coli RNA polymerase.Biochemistry. 2000 Oct 10;39(40):12274-83. doi: 10.1021/bi001433h. Biochemistry. 2000. PMID: 11015206
-
Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation.J Bacteriol. 1998 Jul;180(13):3265-75. doi: 10.1128/JB.180.13.3265-3275.1998. J Bacteriol. 1998. PMID: 9642176 Free PMC article. Review. No abstract available.
-
Transcription activation at Class I CAP-dependent promoters.Mol Microbiol. 1993 May;8(5):797-802. doi: 10.1111/j.1365-2958.1993.tb01626.x. Mol Microbiol. 1993. PMID: 8394979 Review.
Cited by
-
Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA.Nucleic Acids Res. 1995 Jul 11;23(13):2351-60. doi: 10.1093/nar/23.13.2351. Nucleic Acids Res. 1995. PMID: 7630711 Free PMC article.
-
Structure of open promoter complexes with Escherichia coli RNA polymerase as revealed by the DNase I footprinting technique: compilation analysis.Nucleic Acids Res. 1995 Nov 25;23(22):4533-41. doi: 10.1093/nar/23.22.4533. Nucleic Acids Res. 1995. PMID: 8524639 Free PMC article.
-
A cinematographic view of Escherichia coli RNA polymerase translocation.EMBO J. 1989 Sep;8(9):2745-54. doi: 10.1002/j.1460-2075.1989.tb08416.x. EMBO J. 1989. PMID: 2555184 Free PMC article.
-
Kinetic study in vitro of Escherichia coli promoter closure during transcription initiation.Biochem J. 1995 Feb 15;306 ( Pt 1)(Pt 1):123-8. doi: 10.1042/bj3060123. Biochem J. 1995. PMID: 7864798 Free PMC article.
-
Conformational changes in E. coli RNA polymerase during promoter recognition.Nucleic Acids Res. 1993 Dec 11;21(24):5748-53. doi: 10.1093/nar/21.24.5748. Nucleic Acids Res. 1993. PMID: 8284224 Free PMC article.