Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar;41(2):217-220.
doi: 10.1111/cpf.12675. Epub 2020 Dec 5.

Diameter-based measurements of the degree of carotid artery stenosis using ultrasonography

Affiliations

Diameter-based measurements of the degree of carotid artery stenosis using ultrasonography

Annika C Larsson et al. Clin Physiol Funct Imaging. 2021 Mar.

Abstract

Flow velocity measurement by duplex ultrasonography (DUS) is widely accepted as a preoperative method for grading carotid stenoses. Diameter-based grading is used for angiographic methods, but so far the experience is limited regarding diameter-based grading using DUS. In 101 cases with different degrees of carotid stenoses, we compared diameter- and velocity-based grading using DUS and evaluated variability and reproducibility for diameter measurements in 38 of the stenoses. In 18% of the cases, suboptimal image quality with calcifications and acoustic shadowing precluded diameter measurements. In the remaining 83 cases, the agreement between velocity-based and diameter-based grading for distinction between significant and non-significant stenosis was 69% with a kappa value of 0.40. Repeated measurements of diameters showed a coefficient of variation of 10% and intraclass coefficients of correlation of 0.9. We conclude that diameter measurement with DUS can be performed with high reproducibility in most patients with carotid stenosis. These measurements can then be used for calculations of the degree of stenosis, to supplement velocity-based grading. The moderate agreement between diameter-based and flow velocity-based grading cannot easily be explained. Discrepancies probably constitute a mixture of methodological errors and hemodynamic factors and need further evaluation.

Keywords: Doppler; arterial disease; flow velocity; imaging; preoperative investigation.

PubMed Disclaimer

References

REFERENCES

    1. AbuRahma, A. F., Srivastava, M., Stone, P. A., Mousa, A. Y., Jain, A., Dean, L. S., Keiffer, T., & Emmet, M. (2011). Critical appraisal of the carotid duplex consensus criteria in the diagnosis of carotid artery stenosis. Journal of Vascular Surgery, 53, 53-59. https://doi.org/10.1016/j.jvs.2010.07.045
    1. Altman, D. G. (1991) Practical statistics for medical research (pp. 403-409). Chapman & Hall.
    1. Barnett, H. J., Taylor, D. W., Eliasziw, M., Fox, A. J., Ferguson, G. G., Haynes, R. B., Rankin, R. N., Clagett, G. P., Hachinski, V. C., Sackett, D. L., Thorpe, K. E., Meldrum, H. E., & Spence, J. D. (1998). Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. New England Journal of Medicine, 339, 1415-1425. https://doi.org/10.1056/NEJM199811123392002
    1. European Carotid Surgery Trialists' Collaborative Group (1998). Randomised trial of endarterectomy for recently symptomatic carotid stenosis: Final results of the MRC European Carotid Surgery Trial (ECST). Lancet, 351, 1379-1387.
    1. Fleiss, J. L. (1986). The design and analysis of clinical experiments (pp. 1-32). John Wiley.

MeSH terms

LinkOut - more resources