Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jan;43(1):1-12.
doi: 10.1007/s10529-020-03047-0. Epub 2020 Nov 6.

Biosynthesis of magnetic iron oxide nanoparticles: a review

Affiliations
Review

Biosynthesis of magnetic iron oxide nanoparticles: a review

M J Jacinto et al. Biotechnol Lett. 2021 Jan.

Abstract

Nanoparticles promise to revolutionize the way we think of ordinary materials thanks to the new features such small structures exhibit which include strength, durability, optical and magnetics properties. Magnetic iron oxide nanoparticles (IONPs) are a prominent class of NMs because of their potential application in magnetic separation, hyperthermia, targeted drug delivery, and catalysis. Most synthetic nanoparticulate platforms rely on the use of tough chemical procedures associated with unfriendly, harmful and costly reactants. For this reason, bio-inspired approaches have become the most successful alternatives to fabricate nanomaterials in an "eco-friendly" manner, and many bio-protocols that make use of substrates from plants and microorganisms have been successfully applied in the synthesis of magnetic IONPs. In this review, the main biosynthesis protocols applied in the synthesis of iron oxide nanoparticles are discussed. A discussion on the challenges for a second stage perspective which would be a large scale production is also given.

Keywords: Biosynthesis; Biotechnological functional materials; Green chemistry; Iron oxide nanoparticles.

PubMed Disclaimer

References

    1. Abusalem M, Awwad A, Ayad J, Abu-Rayyan A (2019) Green synthesis of α-Fe2O3 nanoparticles using pistachio leaf extract influenced seed germination and seedling growth of tomatos. Jordan J Earth Environ Sci 10:161–166
    1. Aksu Demirezen D, Yilmaz D, Yılmaz Ş (2018) Green synthesis and characterization of iron nanoparticles using Aesculus hippocastanum seed extract. Int J Adv Sci Eng Technol 6:2321–8991
    1. Aksu Demirezen D, Yıldız YŞ, Yılmaz Ş, Demirezen Yılmaz D (2019) Green synthesis and characterization of iron oxide nanoparticles using Ficus carica (common fig) dried fruit extract. J Biosci Bioeng 127:241–245. https://doi.org/10.1016/j.jbiosc.2018.07.024
    1. Alamilla Martínez DG, Rojas-Avelizapa NG, Domínguez-López I, Pool H, Gómez-Ramírez M (2019) Biosynthesis of iron nanoparticles (FeNPs) by Alternaria alternata MVSS-AH-5. Mex J Biotechnol 4:1–14. https://doi.org/10.29267/mxjb.2019.4.4.1
    1. Alphandéry E (2020a) Bio-synthesized iron oxide nanoparticles for cancer treatment. Int J Pharm 586:119472. https://doi.org/10.1016/j.ijpharm.2020.119472 - DOI - PubMed

MeSH terms

LinkOut - more resources