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Case Reports
. 2021 Mar;186(1):109-112.
doi: 10.1007/s11046-020-00505-1. Epub 2020 Nov 6.

COVID-19-Associated Histoplasmosis in an AIDS Patient

Rossana Patricia Basso  1   2 , Vanice Rodrigues Poester  1 , Jéssica Louise Benelli  1 , David A Stevens  3   4 , Heruza Einsfeld Zogbi  1   2 , Izadora Clezar da S Vasconcellos  5 , Alessandro Comarú Pasqualotto  5 , Melissa Orzechowski Xavier  6   7   8
Affiliations
Case Reports

COVID-19-Associated Histoplasmosis in an AIDS Patient

Rossana Patricia Basso et al. Mycopathologia. 2021 Mar.

Abstract

Most reports associating fungal infections with COVID-19 have been cases of invasive aspergillosis. Here, we report a case of severe histoplasmosis and COVID-19 infections in an HIV patient in Rio Grande, Southern Brazil. Histoplasmosis must be included as a diagnostic possibility in opportunistic fungal co-infections in COVID-19 patients with AIDS, mainly in endemic areas.

Keywords: AIDS; COVID-19; Histoplasma capsulatum; Mycoses; SARS-CoV-2.

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Conflict of interest statement

The authors declare that they have no conflict of interest pertaining to this work.

Figures

Fig. 1
Fig. 1
Sputum microscopy showing abundant small oval blastoconidia (arrow) without pseudo-hyphae (Gomori-Grocott stain)
Fig. 2
Fig. 2
Computed tomography of the chest (a) and abdomen (b) of July 17, 2020. c, d Images show follow-up computed tomography performed on September 14, 2020
See this image and copyright information in PMC

References

    1. Coronavirus Worldometer. https://www.worldometers.info/coronavirus/. Accessed 17 Oct 2020
    1. Bartoletti M, Pascale R, Cricca M, Rinaldi M, Maccaro A, Bussini L, et al. Epidemiology of invasive pulmonary aspergillosis among COVID-19 intubated patients: a prospective study. Clin Infect Dis. 2020 doi: 10.1093/cid/ciaa1065. - DOI - PMC - PubMed
    1. Antinori S, Bonazzetti C, Gubertini G, Capetti A, Pagani C, Morena V, et al. Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia? Autoimmun Rev. 2020;19(7):102564. doi: 10.1016/j.autrev.2020.102564. - DOI - PMC - PubMed
    1. Vizcarra P, Pérez-Elías MJ, Quereda C, Moreno A, Vivancos MJ, Dronda F, et al. Description of COVID-19 in HIV-infected individuals: a single-centre, prospective cohort. Lancet HIV. 2020;7(8):e554–e564. doi: 10.1016/S2352-3018(20)30164-8. - DOI - PMC - PubMed
    1. Xu Z, Zhang C, Wang F-S. COVID-19 in people with HIV. Lancet HIV. 2020;7(8):e524–e526. doi: 10.1016/S2352-3018(20)30163-6. - DOI - PMC - PubMed

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