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. 2021 Jan 1;32(1):137-140.
doi: 10.1093/icvts/ivaa233.

First-in-children epicardial mapping of the heart: unravelling arrhythmogenesis in congenital heart disease

Rohit K Kharbanda  1   2 , Mathijs S van Schie  1 , Wouter J van Leeuwen  2 , Yannick J H J Taverne  2 , Charlotte A Houck  1   2 , Janneke A E Kammeraad  3 , Ad J J C Bogers  2 , Natasja M S de Groot  1
Affiliations

First-in-children epicardial mapping of the heart: unravelling arrhythmogenesis in congenital heart disease

Rohit K Kharbanda et al. Interact Cardiovasc Thorac Surg. .

Abstract

Patients with congenital heart disease (CHD) are prone to develop atrial and ventricular arrhythmias. Multiple factors throughout life contribute to arrhythmogenicity substrate such as (i) (longstanding) volume and/or pressure overload, (ii) scar tissue, (iii) ageing-related structural remodelling, (iv) cardiovascular risk factors and (v) tachycardia-induced remodelling. At present, it is unknown whether, and to what extent, paediatric patients with CHD have atrial or ventricular conduction disorders early in life and whether there is a correlation between duration of volume/pressure overload and extensiveness of conduction disorders. To investigate this, we initiated high-resolution intraoperative epicardial mapping in paediatric patients with CHD undergoing primary open-heart surgery.

Keywords: Cardiac atrial mapping; Congenital heart disease; Electrophysiology.

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Figures

Figure 1:
Figure 1:
(A) The mapping electrode array and the predefined atrial and ventricular mapping locations. (B) Epicardial mapping, the corresponding electrograms and colour-coded activation maps. A: atria; Ao: aorta; BB: Bachmann’s bundle; IVC: inferior vena cava; LA: left atrium; LAD: left anterior descending artery; LV: left ventricle; mV: millivolt; RA: right atrium; RV: right ventricle; SVC: superior vena cava; V: ventricles.
See this image and copyright information in PMC

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