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Comment
. 2020 Nov 5;80(3):379-380.
doi: 10.1016/j.molcel.2020.10.020.

A "Sugar-Coated" Proton Pump Comes into Focus: High-Resolution Structure of a Human V-ATPase

Rebecca A Oot  1 , Stephan Wilkens  2
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A "Sugar-Coated" Proton Pump Comes into Focus: High-Resolution Structure of a Human V-ATPase

Rebecca A Oot et al. Mol Cell. .
Free article

Abstract

In this issue of Molecular Cell, Wang et al. (2020a) present near-atomic resolution cryoEM structures of a proton-pumping vacuolar ATPase from human cells, illuminating the glycosylation of integral subunits and identifying a novel and conserved glycolipid ligand.

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