Therapeutic Targets in Chronic Lymphocytic Leukemia

Affiliations

¹ Department of Hematology, Fondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
² Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.

Editorial

Luca Laurenti et al. Cancers (Basel). 2020.

. 2020 Nov 4;12(11):3259.

doi: 10.3390/cancers12113259.

¹ Department of Hematology, Fondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
² Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.

Abstract

Chronic lymphocytic leukemia (CLL) is a common B cell malignancy and is the most common type of adult leukemia in western countries [...].

The authors declare no conflict of interest.

1. Dal-Bo M., Bertoni F., Forconi F., Zucchetto A., Bomben R., Marasca R., Deaglio S., Laurenti L., Efremov D.G., Gaidano G., et al. Intrinsic and Extrinsic Factors Influencing the Clinical Course of B-Cell Chronic Lymphocytic Leukemia: Prognostic Markers with Pathogenetic Relevance. J. Transl. Med. 2009;7:76. doi: 10.1186/1479-5876-7-76. - DOI - PMC - PubMed
1. Hallek M., Shanafelt T.D., Eichhorst B. Chronic Lymphocytic Leukaemia. Lancet. 2018;391:1524–1537. doi: 10.1016/S0140-6736(18)30422-7. - DOI - PubMed
1. Kipps T.J., Stevenson F.K., Wu C.J., Croce C.M., Packham G., Wierda W.G., O’Brien S., Gribben J., Rai K. Correction: Chronic Lymphocytic Leukaemia. Nat. Rev. Dis. Prim. 2017;3:17008. doi: 10.1038/nrdp.2017.8. - DOI - PubMed
1. Guièze R., Wu C.J. Genomic and Epigenomic Heterogeneity in Chronic Lymphocytic Leukemia. Blood. 2015;126:445–453. doi: 10.1182/blood-2015-02-585042. - DOI - PMC - PubMed
1. Sutton L.-A., Rosenquist R. Deciphering the Molecular Landscape in Chronic Lymphocytic Leukemia: Time Frame of Disease Evolution. Haematologica. 2015;100:7–16. doi: 10.3324/haematol.2014.115923. - DOI - PMC - PubMed