Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jan-Feb;30(1):31-37.
doi: 10.1097/CRD.0000000000000370.

Fetal Supraventricular Tachycardia: What the Adult Cardiologist Needs to Know

Affiliations
Review

Fetal Supraventricular Tachycardia: What the Adult Cardiologist Needs to Know

Sutopa Purkayastha et al. Cardiol Rev. 2022 Jan-Feb.

Abstract

Fetal supraventricular tachycardia management is challenging, with consequences for both the fetus and the mother. If left untreated, fetal hydrops may ensue, at which point delivery and treatment of the arrhythmia is preferred. However, if the fetus is not at term nor near-term, significant doses of antiarrhythmics may be needed to achieve adequate transplacental bioavailability. Although digoxin has classically been the mainstay of treatment, the use of flecainide or sotalol as monotherapy or in combination with digoxin is being studied. Interdisciplinary team management and shared decision-making between the physician and patient are key to achieving successful outcomes. Adult cardiologists, particularly inpatient consultation services or through burgeoning cardio-obstetrics programs, may, in some practice settings, be asked to evaluate or comanage pregnant women with fetal arrhythmia.

PubMed Disclaimer

Conflict of interest statement

Disclosures: A.E.B. served as site principal investigator for multicenter trials sponsored by Abbott, AstraZeneca, Sanofi-Aventis, CSL-Behring, for which her institution received compensation and received an honorarium from ClearView Healthcare Partners, LLC. The remaining authors declare no conflict of interest.

Figures

Figure 1:
Figure 1:
Fetal echocardiogram demonstrating a rate of 200 beats per minute (bpm) on the pulse wave Doppler with severe biventricular dysfunction. Normal fetal heart rate ranges from 110–160 bpm, while supraventricular tachycardia from 200–300 bpm. msec, milliseconds.
Figure 2:
Figure 2:
Fetal echocardiogram demonstrating a long ventriculo-atrial (V-A) interval tachycardia. More atrial than ventricular contractions indicates fetal atrial flutter. Msec, milliseconds.
Figure 3:
Figure 3:
Evidence of digoxin effect with “slurred” S waves on the maternal electrocardiogram (inset). Frequent ECG and symptom monitoring are required in transplacental treatment of fetal supraventricular tachycardia due to potential for maternal toxicity with anti-arrhythmics.
Figure 4:
Figure 4:
After transplacental therapy with digoxin and flecainide, a repeat fetal echocardiogram demonstrated a rate of 130 beats per minute (bpm) with 1:1 atrioventricular conduction, consistent with normal sinus rhythm.
Figure 5:
Figure 5:
Overview of maternal evaluation and potential treatment algorithm when caring for pregnant patients with fetal SVT. SVT, supraventricular tachycardia; ECG, electrocardiogram; MFM, maternal-fetal medicine.

Similar articles

Cited by

References

    1. Donofrio MT, Moon-Grady AJ, Hornberger LK, et al. Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association. Circulation 2014;129:2183–242. - PubMed
    1. Detterich JA, Pruetz J, Sklansky MS. Color M-mode sonography for evaluation of fetal arrhythmias. J Ultrasound Med 2012;31:1681–8. - PubMed
    1. Resnik R ed. Creasy and Resnik’s Maternal-Fetal Medicine: Principles and Practice. 8th Edition ed. Elsevier: ——, 2019.
    1. Hornberger LK, Sahn DJ. Rhythm abnormalities of the fetus. Heart, 2007;93:1294–300. - PMC - PubMed
    1. Simpson LL. Fetal supraventricular tachycardias: diagnosis and management. Semin Perinatol 2000;24:360–72. - PubMed

Substances