Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov 10;20(1):1679.
doi: 10.1186/s12889-020-09796-x.

Disability-adjusted life years for respiratory syncytial virus in children under 2 years

Juana Patricia Sánchez Villamil  1 , Fernando P Polack  2 , Jefferson Antonio Buendía  3
Affiliations

Disability-adjusted life years for respiratory syncytial virus in children under 2 years

Juana Patricia Sánchez Villamil et al. BMC Public Health. .

Abstract

Background: Respiratory syncytial virus infection is the leading cause of bronchiolitis in Colombia. There is growing evidence about the impact of Respiratory syncytial virus on society in terms of years of life lost due to this condition. The objective of the present study is to determine the Disability-Adjusted Life Years for respiratory syncytial virus in children under 2 years in Colombia.

Methods: Data from the national epidemiological surveillance system were used to estimate DALYs, calculated from the sum of years of life lost and years lived with disability due to RSV infection in Colombia. A bootstrapped method with 10,000 iterations was used to estimate each statistical parameter using the package DALY calculator in R.

Results: In 2019, 260,873 years of life (CI95% 208,180-347,023) were lost due to RSV bronchiolitis in Colombian children under 2 years. The estimated rate was 20 DALYs / 1000 person-year (95% CI 16-27).

Conclusion: This is the first report estimating the impact of RSV bronchiolitis morbidity and mortality in Colombia. The findings of the present study suggest that the actual burden and cost of bronchiolitis due to RSV is high. Prevention strategies, such as RSV vaccination, to reduce morbidity associated with RSV infection should be encouraged in our country.

Keywords: Colombia; Global burden of disease; Respiratory syncytial virus.

PubMed Disclaimer

Conflict of interest statement

None to declare.

Figures

Fig. 1
Fig. 1
DALYs by outcome and age
Fig. 2
Fig. 2
Results of sensitivity analysis: Mapped standardized regression coefficients
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010;375(9725):1545–1555. doi: 10.1016/S0140-6736(10)60206-1. - DOI - PMC - PubMed
    1. Hall CB, Simoes EA, Anderson LJ. Clinical and epidemiologic features of respiratory syncytial virus. Curr Top Microbiol Immunol. 2013;372:39–57. - PubMed
    1. Sommer C, Resch B, Simoes EA. Risk factors for severe respiratory syncytial virus lower respiratory tract infection. Open Microbiol J. 2011;5:144–154. doi: 10.2174/1874285801105010144. - DOI - PMC - PubMed
    1. Peñaloza R, Salamanca B, Rodriguez J, Beltran A. Estimación de la carga de enfermedad para Colombia, 2010. 2014(Editorial Pontificia Universidad Javeriana).
    1. Mathers CD VT, Lopez AD, Salomon J, Ezzati M. National Burden of Disease Studies: A Practical Guide: Global Program on Evidence for Health Policy. Geneva: World Health Organization.; 2001 [Available from: http://www.who.int/healthinfo/nationalburdenofdiseasemanual.pdf.