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Comment
. 2021 Feb;18(2):65-66.
doi: 10.1038/s41571-020-00450-4.

Translating noninvasive molecular responses into clinical reality for cancer immunotherapy

Joseph C Murray  1   2 , Valsamo Anagnostou  3   4
Affiliations
Comment

Translating noninvasive molecular responses into clinical reality for cancer immunotherapy

Joseph C Murray et al. Nat Rev Clin Oncol. 2021 Feb.
No abstract available

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Comment on

  • Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition.
    Nabet BY, Esfahani MS, Moding EJ, Hamilton EG, Chabon JJ, Rizvi H, Steen CB, Chaudhuri AA, Liu CL, Hui AB, Almanza D, Stehr H, Gojenola L, Bonilla RF, Jin MC, Jeon YJ, Tseng D, Liu C, Merghoub T, Neal JW, Wakelee HA, Padda SK, Ramchandran KJ, Das M, Plodkowski AJ, Yoo C, Chen EL, Ko RB, Newman AM, Hellmann MD, Alizadeh AA, Diehn M. Nabet BY, et al. Cell. 2020 Oct 15;183(2):363-376.e13. doi: 10.1016/j.cell.2020.09.001. Epub 2020 Oct 1. Cell. 2020. PMID: 33007267 Free PMC article.

References

    1. Anagnostou, V. et al. Dynamics of tumor and immune responses during immune checkpoint blockade in non-small cell lung cancer. Cancer Res. 79, 1214–1225 (2018). - DOI
    1. Bratman, S. V. et al. Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab. Nat. Cancer 1, 873–881 (2020). - DOI
    1. Zhang, Q. et al. Prognostic and predictive impact of circulating tumor DNA in patients with advanced cancers treated with immune checkpoint blockade. Cancer Discov. CD-20-0047 (2020).
    1. Anagnostou, V. et al. Evolution of neoantigen landscape during immune checkpoint blockade in non–small cell lung cancer. Cancer Discov. 7, 264–276 (2017). - DOI
    1. Yost, K. E. et al. Clonal replacement of tumor-specific T cells following PD-1 blockade. Nat. Med. 25, 1251–1259 (2019). - DOI

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