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. 2020 Nov 6;12(11):3405.
doi: 10.3390/nu12113405.

Extractable and Non-Extractable Antioxidants Composition in the eBASIS Database: A Key Tool for Dietary Assessment in Human Health and Disease Research

Jenny Plumb  1 , Alessandra Durazzo  2 , Massimo Lucarini  2 , Emanuela Camilli  2 , Aida Turrini  2 , Luisa Marletta  2 , Paul Finglas  1
Affiliations

Extractable and Non-Extractable Antioxidants Composition in the eBASIS Database: A Key Tool for Dietary Assessment in Human Health and Disease Research

Jenny Plumb et al. Nutrients. .

Abstract

The antioxidant properties of foods are crucial in nutrition, food chemistry, and medicine studies but are often underestimated, with significant amounts of bioactive compounds containing physiological and biochemical properties remaining in the residue from extraction as non-extractable antioxidants. Over the last decade, extractable and non-extractable compounds have become key in the evaluation/determination of the antioxidant properties of food matrices because of their relevance in human health. This has led to the need to include extractable and non-extractable antioxidants in comprehensive and harmonized food composition databases for a wide range of applications within research, food, pharmaceutical, nutraceutical, and cosmeceutical areas. Additionally, the databases are invaluable as part of the health claims application process. eBASIS, (Bioactive Substances in Food Information System) a comprehensive database containing quality-evaluated scientific data, covering the composition of bioactive compounds present in foods, has flexible structures, allowing it to be extended to include newly emerging data on extractable and non-extractable compounds. Search criteria were developed and defined for compiling suitable peer-reviewed literature. Data quality assessment methods were established for the addition of composition data and antioxidant activity, with a focus on various parameters including: the extraction procedure, the antioxidant measurements, the expression of results. A total of 437 quality-evaluated datapoints on the composition of extractable and/or non-extractable compounds were entered into the database. This database update represents one of the first examples of building a database dedicated to antioxidant properties. This expansion of eBASIS provides a novel and unique tool for nutritionists, dietitians, researchers to use for a wide range of applications, such as dietary assessment, exposure studies and epidemiological studies, and may contribute to an increase in high-bioactive food consumption by consumers.

Keywords: antioxidant properties; bioactive compounds; dietary assessment; dietary intake; eBASIS; extractable compounds; human health; non-extractable compounds; nutrition knowledge.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow diagram showing selection of studies for data entry.
Figure 2
Figure 2
(a) Composition information section of eBASIS input form for data entry for EPP; (b) proposed model for input form for EPP, in fresh weight (FW) material, using Ferric Reducing Antioxidant Power (FRAP) assay.
Figure 3
Figure 3
Creation of eBASIS reports.
See this image and copyright information in PMC

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