Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul;45(4):101560.
doi: 10.1016/j.clinre.2020.10.005. Epub 2020 Nov 8.

Impact of the first Covid-19 outbreak on liver transplantation activity in France: A snapshot

Célia Turco  1 , Chetana Lim  2 , Olivier Soubrane  3 , Géraldine Malaquin  4 , François Kerbaul  5 , Olivier Bastien  4 , Filomena Conti  6 , Olivier Scatton  7
Affiliations

Impact of the first Covid-19 outbreak on liver transplantation activity in France: A snapshot

Célia Turco et al. Clin Res Hepatol Gastroenterol. 2021 Jul.

Abstract

Background: The global pandemic of Coronavirus Disease 2019 (COVID-19) has potentially affected liver transplantation (LT) programs worldwide. The aim of this study was to determine whether the COVID-19 outbreak affected organ donation and LT activity in France.

Methods: Data on the number of brain-dead donor procurements and adult liver transplantations were compared between two periods (1st January- 31st May 2019 vs. 1st January-31st May 2020).

Main findings: There was a 28% decrease in the number of organ donations in 2020 (543 in 2020vs. 752 organ donations in 2019). A 22% decrease in the number of liver transplantations was also observed: 435 in 2020 vs. 556 LTs in 2019. Overall, the North East area which was the main COVID-19 cluster area, had > 25% decrease of the multiorgan procurement (-33% compared to 2019), and liver transplantation (-26% compared to 2019) activities in 2020 CONCLUSION: This analysis confirmed that during the COVID-19 outbreak there was a significant decrease in the number of organ donations and liver transplantations performed in France.

Keywords: coronavirus; liver procurement; liver transplantation.

PubMed Disclaimer

Conflict of interest statement

None.

Figures

Figure 1
Figure 1
2020 COVID-19 pandemic in France (black) and the 16 adult liver transplantation centers (yellow).
Figure 2
Figure 2
Time variations of the organ procurement (A) and liver transplantation (B) activities.
Figure 3
Figure 3
Regional variations of the organ procurement activity. Variations shown in regard to: (A) the percentage of decrease in organ procurement, (B) the number of organ procurement.
Figure 4
Figure 4
Regional and center variations of the liver transplantation program activity. Variations shown in regard to: (A) the percentage of decrease in liver transplantations at a regional level, (B) the number of liver transplantations at a regional level, (C) the percentage of decrease in number of liver transplantations at a center level, (D) the number of liver transplantations at a center level.
See this image and copyright information in PMC

References

    1. WHO COVID-19 Dashboard. Available on: https://covid19.who.int/.
    1. Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet Lond Engl. 15. 2020;395(10223):497–506. - PMC - PubMed
    1. COVID-19 situation reports. Available on: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situatio....
    1. Infection au nouveau Coronavirus (SARS-CoV-2), COVID-19, France et Monde [Internet]. Available on: /maladies-et-traumatismes/maladies-et-infections-respiratoires/infection-a-coronavirus/articles/infection-au-nouveau-coronavirus-sars-cov-2-covid-19-france-et-monde.
    1. COvid-19 - Asso - STF [Internet]. Available on: https://www.transplantation-francophone.org/covid-19.