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. 2020 Dec 1;117(48):30009-30011.
doi: 10.1073/pnas.2021128117. Epub 2020 Nov 11.

In fatal COVID-19, the immune response can control the virus but kill the patient

Arturo Casadevall  1 , Liise-Anne Pirofski  2
Affiliations

In fatal COVID-19, the immune response can control the virus but kill the patient

Arturo Casadevall et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no competing interest.

Figures

Fig. 1.
Fig. 1.
Proposed scheme for the progression and outcomes of COVID-19 from the viewpoint of the damage−response of pathogenesis (24). According to the damage−response framework, the relevant outcome is the amount of host damage endured by the host during the host−microbe interaction. Considering damage as a function of time, death occurs in those individuals who suffer irreparable tissue damage, which appears to be mediated largely by the inflammatory response to SARS-Cov-2.
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References

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