Macrocirculation and Microcirculation: The "Batman and Superman" Story of Critical Care Resuscitation

Ashish K Khanna^{1

2}, Kunal Karamchandani³

Affiliations

¹ From the Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest School of Medicine, Wake Forest Baptist Health Network, Winston-Salem, North Carolina.
² Outcomes Research Consortium, Cleveland, Ohio.
³ Department of Anesthesiology & Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Review

Ashish K Khanna et al. Anesth Analg. 2021 Jan.

. 2021 Jan;132(1):280-283.

doi: 10.1213/ANE.0000000000005272.

Ashish K Khanna^{1

2}, Kunal Karamchandani³

¹ From the Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest School of Medicine, Wake Forest Baptist Health Network, Winston-Salem, North Carolina.
² Outcomes Research Consortium, Cleveland, Ohio.
³ Department of Anesthesiology & Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.

No abstract available

Comment in

Macrocirculation and Microcirculation in Septic Shock.
Furst B, Bughrara N, Musuku SR. Furst B, et al. Anesth Analg. 2021 Sep 1;133(3):e37-e38. doi: 10.1213/ANE.0000000000005630. Anesth Analg. 2021. PMID: 34403395 No abstract available.
In Response.
Karamchandani K. Karamchandani K. Anesth Analg. 2021 Sep 1;133(3):e38-e39. doi: 10.1213/ANE.0000000000005631. Anesth Analg. 2021. PMID: 34403396 No abstract available.

1. Rhodes A, Evans LE, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017;43:304–377.
1. Dünser MW, Takala J, Brunauer A, Bakker J. Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Crit Care. 2013;17:326.
1. Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med. 2004;32:1825–1831.
1. Hilty MP, Guerci P, Ince Y, Toraman F, Ince C. MicroTools enables automated quantification of capillary density and red blood cell velocity in handheld vital microscopy. Commun Biol. 2019;2:217.
1. Tanaka S, Harrois A, Nicolaï C, et al. Qualitative real-time analysis by nurses of sublingual microcirculation in intensive care unit: the MICRONURSE study. Crit Care. 2015;19:388.