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Editorial
. 2020 Oct;8(19):1256.
doi: 10.21037/atm-2020-70.

New solutions to old problems-metabolic acidosis in chronic kidney disease

John Sy  1   2 , Joline L T Chen  1   2 , Kamyar Kalantar-Zadeh  1   2
Affiliations
Editorial

New solutions to old problems-metabolic acidosis in chronic kidney disease

John Sy et al. Ann Transl Med. 2020 Oct.
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm-2020-70). KKZ reports personal fees from Abbott, personal fees from Abbvie, personal fees from Alexion, personal fees from Amgen, personal fees from Astra-Zeneca, personal fees from Aveo, personal fees from Chugai, other from DaVita, personal fees from Fresenius Medical Services, personal fees from Genentech, personal fees from Haymarket, personal fees from Hospira, personal fees from Kabi, personal fees from Keryx, personal fees from Navartis, personal fees from Pfizer, personal fees from Relypsa, personal fees from Resverlogix, personal fees from Sandoz, personal fees from Sanofi, personal fees from Shire, personal fees from Vifor, personal fees from ZS-Pharma, personal fees from UpToDate, grants and personal fees from National Institutes of Health, personal fees from Baxter, personal fees from Dr Schaer, personal fees from PCORI, personal fees from Amag Pharma, outside the submitted work; The other authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Mechanisms by which metabolic acidosis may induce protein energy malnutrition. Adapted from (5).
See this image and copyright information in PMC

Comment on

References

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    1. Kraut JA, Madias NE. Adverse Effects of the Metabolic Acidosis of Chronic Kidney Disease. Adv Chronic Kidney Dis 2017;24:289-97. 10.1053/j.ackd.2017.06.005 - DOI - PubMed
    1. Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Association of serum bicarbonate levels with mortality in patients with non-dialysis-dependent CKD. Nephrol Dial Transplant 2009;24:1232-7. 10.1093/ndt/gfn633 - DOI - PMC - PubMed
    1. Kopple JD, Kalantar-Zadeh K, Mehrotra R. Risks of chronic metabolic acidosis in patients with chronic kidney disease. Kidney Int Suppl 2005;67:S21-7. 10.1111/j.1523-1755.2005.09503.x - DOI - PubMed