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Editorial
. 2020 Oct;8(19):1258.
doi: 10.21037/atm-20-1933.

Comment on a recent genetic study on the risk profile of Hirschsprung's disease from a pediatric surgeon's perspective

Nana Nakazawa-Tanaka  1   2 , Geoffrey J Lane  2 , Atsuyuki Yamataka  2
Affiliations
Editorial

Comment on a recent genetic study on the risk profile of Hirschsprung's disease from a pediatric surgeon's perspective

Nana Nakazawa-Tanaka et al. Ann Transl Med. 2020 Oct.
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm-20-1933). The authors have no conflicts of interest to declare.

Comment on

  • Molecular Genetic Anatomy and Risk Profile of Hirschsprung's Disease.
    Tilghman JM, Ling AY, Turner TN, Sosa MX, Krumm N, Chatterjee S, Kapoor A, Coe BP, Nguyen KH, Gupta N, Gabriel S, Eichler EE, Berrios C, Chakravarti A. Tilghman JM, et al. N Engl J Med. 2019 Apr 11;380(15):1421-1432. doi: 10.1056/NEJMoa1706594. N Engl J Med. 2019. PMID: 30970187 Free PMC article.

References

    1. Meinds RJ, van der Steeg AFW, Sloots CEJ, et al. Long-term functional outcomes and quality of life in patients with Hirschsprung's disease. Br J Surg 2019:106:499-507. 10.1002/bjs.11059 - DOI - PMC - PubMed
    1. Ruttenstock E, Puri P. A meta-analysis of clinical outcome in patients with total intestinal aganglionosis. Pediatr Surg Int 2009:25:833-9. 10.1007/s00383-009-2439-2 - DOI - PubMed
    1. Obata S, Ieiri S, Akiyama T, et al. Nationwide survey of outcome in patients with extensive aganglionosis in Japan. Pediatr Surg Int 2019:35:547-50. 10.1007/s00383-019-04462-9 - DOI - PubMed
    1. Laughlin DM, Friedmacher F, Puri P. Total colonic aganglionosis: a systematic review and meta-analysis of long-term clinical outcome. Pediatr Surg Int 2012;28:773-9. 10.1007/s00383-012-3117-3 - DOI - PubMed
    1. Tilghman JM, Ling AY, Turner TN, et al. Molecular Genetic Anatomy and Risk Profile of Hirschsprung's Disease. N Engl J Med 2019;380:1421-32. 10.1056/NEJMoa1706594 - DOI - PMC - PubMed