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. 2020 Oct 19;12(1):e1-e8.
doi: 10.4102/phcfm.v12i1.2474.

Prevalence, healthcare costs and management of non-communicable diseases in people living with human immunodeficiency virus: A scoping review

Laston Gonah  1 , Indres Moodley, Khumbulani Hlongwana
Affiliations

Prevalence, healthcare costs and management of non-communicable diseases in people living with human immunodeficiency virus: A scoping review

Laston Gonah et al. Afr J Prim Health Care Fam Med. .

Abstract

Background: Coexistence of human immunodeficiency virus (HIV) and non-communicable diseases (NCDs) is an important public health issue of increasing concern. However, the prevalence, healthcare costs and management protocols for NCDs in people living with HIV (PLHIV) remain unclear in most settings.

Aim: To scope evidence on prevalence, healthcare costs and disease management protocols associated with NCDs in PLHIV from studies published before July 2019.

Methods: Electronic databases were searched for published articles, and reference lists were checked for relevant studies. Key terms included were HIV/AIDS, co-morbidity or multi-morbidity, NCDs, healthcare costs, treatment protocols, diabetes mellitus, hypertension in various combinations.

Results: A total of 152 records were assessed, and thereafter 25 studies were included in the final review after all the elimination. Twelve of the 25 studies mostly reported prevalence of NCDs in PLHIV, 4 reported impact of HIV-NCD co-morbidity on healthcare costs and 1 reported management protocols and capacity of antiretroviral therapy (ART) sites to manage HIV-NCD co-morbidity.

Conclusions: Results showed higher prevalence rates of diabetes mellitus and hypertension in PLHIV compared with HIV-negative people. However, there was inconsistency in NCD prevalence data from studies conducted in sub-Saharan African (SSA) countries, and limited research evidence on capacity of ART sites to manage NCDs in PLHIV. Low prevalence rates of NCDs reported in SSA countries could be an indication of limited capacity to screen for NCDs because of the influence of health system and/or patient-level factors. Most studies were generally limited to cross-sectional studies, with very few interventional, longitudinal studies.

Keywords: HIV/AIDS; co-morbidity; diabetes mellitus; healthcare costs; hypertension; multi-morbidity; non-communicable diseases; prevalence.

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Conflict of interest statement

The authors have declared that no competing interest exists.

Figures

FIGURE 1
FIGURE 1
Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram summarising the search process and the selection results.
See this image and copyright information in PMC

References

    1. UNAIDS Global report: UNAIDS report on the global AIDS epidemic 2013. Geneva: Joint United Nations Programme on HIV; 2013.
    1. Joint United Nations Programme on HIV/AIDS (UNAIDS) Global HIV & AIDS statistics – 2018 fact sheet [homepage on the Internet]. Joint United Nations Programme on HIV/AIDS; 2018. Available from: https://www.unaids.org/en/resources/fact-sheet
    1. Narayan KV, Miotti P, Anand NP, et al. . HIV and noncommunicable disease comorbidities in the era of antiretroviral therapy: A vital agenda for research in low-and middle-income country settings. J Acquir Immune Defic Syndr. 2014;67(S1):S2–S7. 10.1097/qai.0000000000000267 - DOI - PubMed
    1. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group . Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. ACP. 2009;151(4):264–269. 10.7326/0003-4819-151-4-200908180-00135 - DOI - PubMed
    1. Samson D, Schoelles KM. Chapter 2: Developing the topic and structuring systematic reviews of medical tests: Utility of PICOTS, analytic frameworks, decision trees, and other frameworks In: Chang SM, Matchar DB, Smetana GW, et al., editors. Methods guide for medical test reviews [homepage on the Internet]. Rockville, MD: Agency for Healthcare Research and Quality (US); 2012. Available from: https://www.ncbi.nlm.nih.gov/sites/books/NBK98235/ - PubMed

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