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Review
. 2020 Nov 13;18(1):110.
doi: 10.1186/s12958-020-00668-y.

Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health

Iman Halvaei  1 , Julia Litzky  2 , Navid Esfandiari  3
Affiliations
Review

Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health

Iman Halvaei et al. Reprod Biol Endocrinol. .

Abstract

Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health.

Keywords: Aging; Live birth; Male age; Pregnancy; Sperm.

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Conflict of interest statement

The authors declare that they have no competing interests.

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