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. 2021 Mar 1;22(3):197-203.
doi: 10.2459/JCM.0000000000001135.

Evaluation of P-wave dispersion in patients with newly diagnosed coronavirus disease 2019

Mustafa Yenerçağ  1 , Uğur Arslan  1 , Onur O Şeker  1 , Seçkin Dereli  2 , Ahmet Kaya  2 , Mustafa Doğduş  3 , Çağatay E Öztürk  4 , Çetin K Akpınar  5 , Ahmet Şen  4
Affiliations

Evaluation of P-wave dispersion in patients with newly diagnosed coronavirus disease 2019

Mustafa Yenerçağ et al. J Cardiovasc Med (Hagerstown). .

Abstract

Aim: The aim of the current study was to evaluate P-wave dispersion (PWD) as a predictor of atrial fibrillation in patients with newly diagnosed COVID-19. In addition, the relationship between the PWD and inflammation parameters was investigated.

Methods: A total of 140 newly diagnosed COVID-19 patients and 140 age- and sex-matched healthy individuals were included in the study. The risk of atrial fibrillation was evaluated by calculating the electrocardiographic PWD. C-reactive protein (CRP), white blood cell, neutrophil and neutrophil-to-lymphocyte ratio (NLR) were measured in patients with newly diagnosed COVID-19.

Results: PWD, white blood cell, NLR and CRP levels were significantly higher in the COVID-19 group than the control group. There was a significant positive correlation between PWD and CRP level (rs = 0.510, P < 0.001) and NLR in COVID-19 group (rs = 0.302, P = 0.001). In their follow-up, 13 (9.3%) patients, 11 of whom were in the ICU, developed new atrial fibrillation.

Conclusion: Our study showed for the first time in literature that the PWD, evaluated electrocardiographically in patients with newly diagnosed COVID-19, was prolonged compared with normal healthy individuals. A positive correlation was found between PWD, CRP level and NLR. We believe that pretreatment evaluation of PWD in patients with newly diagnosed COVID-19 would be beneficial for predicting atrial fibrillation risk.

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References

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