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Comment
. 2020 Dec;42(6):909-910.
doi: 10.1097/FTD.0000000000000809.

Comment on "Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples"

Uwe Liebchen  1 , Christoph Dorn  2 , Martin Kees  3 , Selina Schiesser  4 , Florian Hitzenbichler  4 , Frieder Kees  2 , Michael Paal  5
Affiliations
Comment

Comment on "Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples"

Uwe Liebchen et al. Ther Drug Monit. 2020 Dec.
No abstract available

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References

    1. Al-Shaer MH, Alghamdi WA, Graham E, et al. Meropenem, cefepime, and piperacillin protein binding in patient samples. Ther Drug Monit. 2020;42:129–132.
    1. Schleibinger M, Steinbach CL, Töpper C, et al. Protein binding characteristics and pharmacokinetics of ceftriaxone in ICU patients. Br J Clin Pharmacol. 2015;80:525–533.
    1. Wong G, Briscoe S, Adnan S, et al. Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations? Antimicrob Agents Chemother. 2013;57:6165–6170.
    1. Colman S, Stove V, Waele JD, et al. Measuring unbound versus total piperacillin concentrations in plasma of critically ill patients: methodological issues and relevance. Ther Drug Monit. 2019;41:325–330.
    1. Dorn C, Schießer S, Wulkersdorfer B, et al. Determination of free clindamycin, flucloxacillin or tedizolid in plasma: pay attention to physiological conditions when using ultrafiltration. Biomed Chromatogr. 2020;34:e4820.

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