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Review
. 2021 Jan-Feb:56:70-79.
doi: 10.1016/j.pedn.2020.10.020. Epub 2020 Oct 22.

Human Coronaviruses SARS-CoV, MERS-CoV, and SARS-CoV-2 in Children

Elahe Aleebrahim-Dehkordi  1 , Faezeh Soveyzi  2 , Niloofar Deravi  3 , Zahra Rabbani  2 , Amene Saghazadeh  4 , Nima Rezaei  5
Affiliations
Review

Human Coronaviruses SARS-CoV, MERS-CoV, and SARS-CoV-2 in Children

Elahe Aleebrahim-Dehkordi et al. J Pediatr Nurs. 2021 Jan-Feb.

Abstract

The novel coronavirus, known as 2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an epidemic with high mortality and morbidity since December 2019, in Wuhan, China. The infection has now been transmitted to more than 210 countries worldwide and caused more than 200,000 deaths. Similar to other coronaviruses such as Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 appears to less commonly affect pediatrics and to cause less severe disease along with fewer symptoms compared to adults. Available data suggest that the pediatric population is just as likely as adults to become infected with SARS-CoV-2. However, they may be asymptotic or have milder symptoms than adults; they can be potential carriers of the disease. This article reviews the present understanding of SARS-CoV-2 infection in the pediatric age group in comparison with MERS-CoV and SARS-CoV.

Keywords: COVID-19; Children; Clinical manifestations; Human coronaviruses; MERS-CoV; SARS-CoV; SARS-CoV-2.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no competing interests.

References

    1. (CDC) CfDCaP . 2003. Interim Domestic Guidance on the Use of Respirators to Prevent Transmission of SARS 6 May.https://www.cdc.gov/sars/clinical/respirators.html Available from.
    1. (CDC) CfDCaP . 2014. Interim Infection Prevention and Control Recommendations for Hospitalised Patients with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) February 13.
    1. (CDC) CfDCaP . 2020. Coronavirus disease 2019 (COVID-19) - social distancing, quarantine, and isolation.https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/social-di... 15 July 2020 [Available from.
    1. (CDC) CfDCaP . 2020. Coronavirus disease 2019 (COVID-19). Use of cloth face coverings to help slow the spread of COVID-19 9 April.https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/diy-cloth... Available from.
    1. (PICS) PICS . 2020. PICS Statement: Increased number of reported cases of novel presentation of multi-system inflammatory disease. 29 April.

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