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Comparative Study
. 2021 Jan;99(1):115228.
doi: 10.1016/j.diagmicrobio.2020.115228. Epub 2020 Sep 30.

Analysis of sputum/tracheal aspirate and nasopharyngeal samples for SARS-CoV-2 detection by laboratory-developed test and Panther Fusion system

Phyu M Thwe  1 , Ping Ren  2
Affiliations
Comparative Study

Analysis of sputum/tracheal aspirate and nasopharyngeal samples for SARS-CoV-2 detection by laboratory-developed test and Panther Fusion system

Phyu M Thwe et al. Diagn Microbiol Infect Dis. 2021 Jan.

Abstract

In this study, 127 sputum/tracheal aspirate specimens were evaluated by a laboratory-developed real-time RT-PCR method and Fusion SARS-CoV-2 assay. These specimens were collected from the patients who have nasopharyngeal swab (NPS) samples being used for SARS-CoV-2 detection previously or simultaneously. The overall agreement was 96% between the lower respiratory tract (LRT) and NPS samples, suggesting that LRT specimens could be an option for patients who develop a productive cough or those receiving invasive mechanical ventilation.

Keywords: COVID-19; Lower respiratory tract; Nasopharyngeal swab sample; SARS-CoV-2; Sputum; Tracheal aspirate.

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