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. 2021 Jun;23(6):1054-1066.
doi: 10.1007/s12094-020-02491-8. Epub 2020 Nov 16.

Multidisciplinary consensus on cancer management during pregnancy

A Cubillo  1 , S Morales  2 , E Goñi  3 , F Matute  4 , J L Muñoz  5 , D Pérez-Díaz  6 , J de Santiago  7 , Á Rodríguez-Lescure  8   9
Affiliations

Multidisciplinary consensus on cancer management during pregnancy

A Cubillo et al. Clin Transl Oncol. 2021 Jun.

Abstract

Cancer during pregnancy is a challenge for multi- and interdisciplinary collaboration due to the diagnostic, prognostic and therapeutic implications, the need for an integrated harmonization of medical action for the pregnant patient and the embryo or foetus and the characteristics of each gestational period, which will determine the protocol to be proposed and its limitations. For this reason, a group of experts appointed by participating scientific societies, which includes the Spanish Society of Medical Oncology (Sociedad Española de Oncología Médica-SEOM), the Spanish Association of Surgeons (Asociación Española de Cirujanos-AEC), the Spanish Society of Gynaecology and Obstetrics (Sociedad Española de Ginecología y Obstetricia-SEGO), the Spanish Society of Nuclear Medicine and Molecular Imaging (Sociedad Española de Medicina Nuclear e Imagen Molecular-SEMNIM), the Spanish Society of Oncological Radiotherapy (Sociedad Española de Oncología Radioterápica-SEOR) and the Spanish Society of Medical Radiology (Sociedad Española de Radiología Médica-SERAM), have worked together to establish consensus recommendations that allow the harmonization of management and ultimately the optimization of the healthcare of pregnant patients with cancer. When cancer is detected in a pregnant woman, the week of gestation in which the diagnosis is made must be considered, as well as the characteristics of the tumour. It is strongly recommended that a multidisciplinary team assesses the situation and guides the patient and her family during the informing, diagnosis and treatment process. Likewise, the foetus should be monitored and managed by specialized obstetricians who are part of a multidisciplinary cancer committee.

Keywords: Antineoplastic agents; Child development; Diagnosis; Follow-up; Prenatal care; Radiotherapy; Surgery; Systemic therapies.

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Conflict of interest statement

The authors declare that they did not have any conflict of interest related with this project.

Figures

Fig. 1
Fig. 1
Recommendations for different diagnostic tests during pregnancy according to trimester. SLNB selective sentinel lymph node biopsy, PET positron emission tomography. Green: recommended; Yellow: depending on gestational age and tumour location; Red: not recommended
Fig. 2
Fig. 2
Flowchart of the multidisciplinary team involved during the informing, diagnosis and treatment of pregnant patients with cancer
See this image and copyright information in PMC

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