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. 2020 Oct 23:11:567309.
doi: 10.3389/fgene.2020.567309. eCollection 2020.

Y-Chromosome Genetic Analysis of Modern Polish Population

Łukasz Grochowalski  1 , Justyna Jarczak  1   2 , Maria Urbanowicz  1 , Marcin Słomka  1   2 , Maria Szargut  3   4 , Paulina Borówka  5 , Marta Sobalska-Kwapis  1   2 , Błażej Marciniak  1   2 , Andrzej Ossowski  3   4 , Wiesław Lorkiewicz  5 , Dominik Strapagiel  1   2
Affiliations

Y-Chromosome Genetic Analysis of Modern Polish Population

Łukasz Grochowalski et al. Front Genet. .

Abstract

The study presents a full analysis of the Y-chromosome variability of the modern male Polish population. It is the first study of the Polish population to be conducted with such a large set of data (2,705 individuals), which includes genetic information from inhabitants of all voivodeships, i.e., the first administrative level, in the country and the vast majority of its counties, i.e., the second level. In addition, the available data were divided into clusters corresponding to more natural geographic regions. Genetic analysis included the estimation of F ST distances, the visualization with the use of multidimensional scaling plots and analysis of molecular variance. Y-chromosome binary haplogroups were classified and visualized with the use of interpolation maps. Results showed that the level of differentiation within Polish population is quite low, but some differences were indicated. It was confirmed that the Polish population is characterized by a high degree of homogeneity, with only slight genetic differences being observed at the regional level. The use of regional clustering as an alternative to counties and voivodeships provided a more detailed view of the genetic structure of the population. Those regional differences identified in the present study highlighted the need for additional division of the population by cultural and ethnic criteria in such studies rather than just by geographical or administrative regionalization.

Keywords: Polish population; SNPs; Y-chromosome; haplogroups; microarray analysis; regions of Poland.

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Figures

FIGURE 1
FIGURE 1
Interpolation maps for the two main haplogroups (R and I) with the division (in case of hg R) into subhaplogroups R1a and R1b observed in the Polish population.
FIGURE 2
FIGURE 2
Interpolation maps for the other main haplogroups (N, E and J) observed in the Polish population.
FIGURE 3
FIGURE 3
Two-dimensional MDS plot of Polish voivodeship populations based on pairwise FST values.
FIGURE 4
FIGURE 4
Two-dimensional MDS plot of cluster populations based on pairwise FST values.
See this image and copyright information in PMC

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