The Diagnostic Pitfalls of Mucormycosis
- PMID: 33194153
- PMCID: PMC7643780
- DOI: 10.4084/MJHID.2020.079
The Diagnostic Pitfalls of Mucormycosis
Abstract
Background: Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales.
Case report: We describe a case of of Lichtheimia corymbifera infection in a 15-year-old child with B-cell-Non-Hodgkin Lymphoma (B-NHL) involving lung, kidney and thyroid that initially was diagnosed as probable aspergillosis delaying the effective therapy for mucormycosis.
Conclusions: This case showed that also the intensive chemotherapy for B-NHL may represent a risk factor for mucormycosis infection. Liposomal amphotericin B and surgery remain the key tools for the successful treatment of this aggressive disease.
Keywords: Fungal infection; Mucormycosis; Pediatric non Hodgkin lymphoma.
Conflict of interest statement
Competing interests: The authors declare no conflict of Interest.
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References
-
- Francis JR, Villanueva P, Bryant P, Blyth CC. Mucormycosis in children: review and recommendations for management. J Pediatric Infect Dis Soc. 2017;00:1–6. - PubMed