Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Oct 30:8:572923.
doi: 10.3389/fchem.2020.572923. eCollection 2020.

Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy

Affiliations
Review

Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy

Fosca Errante et al. Front Chem. .

Abstract

Among the many aspects that contribute to the wellness of each individual, healthy and younger-looking skin play a relevant role, as clearly shown by the important growth of the skin-care products market observed in recent years. In this scenario, the field of cosmeceuticals appears particularly promising, being based on cosmetic products containing active ingredients. Among these, several peptides were proposed for cosmeceutical applications, thanks to their specific interaction with biological targets. In this mini-review, we report some of the most investigated and used peptides for cosmetic formulations, taking into account that cosmeceutical peptides are basically divided into three main categories (i.e., neurotransmitter inhibitors, carriers, and signal peptides). Special attention was payed to the scientific studies supporting the claimed biological activity of these peptides, as a fundamental aspect that should underpin the growth of this field in the framework of a sustainable wellness economy.

Keywords: carrier peptides; neurotransmitter peptide inhibitors; peptide-based cosmetics; signal peptides; sustainable wellness economy.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Relevant peptides in commercially available cosmeceuticals.
Figure 2
Figure 2
Influence of SA1-III peptide (KP1) on collagen turnover in human dermis.

References

    1. Arul V., Gopinath D., Gomathi K., Jayakumar R. (2005). Biotinylated GHK peptide incorporated collagenous matrix: a novel biomaterial for dermal wound healing in rats. J. Biomed. Mater. Res. B Appl. Biomater. 3B, 383–391. 10.1002/jbm.b.30246 - DOI - PubMed
    1. Blanes-Mira C., Clemente J., Jodas G., Gil A., Fernandez-Ballester G., Ponsati B., et al. . (2002). A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int. J. Cosmet. Sci. 24, 303–310. 10.1046/j.1467-2494.2002.00153.x - DOI - PubMed
    1. Campbell J. D., McDonough J. E., Zeskind J. E., Hackett T. L., Pechkovsky D. V., Brandsma C., et al. . (2012). A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK. Genome Med. 4:67. 10.1186/gm367 - DOI - PMC - PubMed
    1. Cauchard J., Berton A., Godeau G., Hornebeck W., Bellon G. (2004). Activation of latent transforming growth factor beta 1 and inhibition of matrix metalloprotease activity by a thrombospondin-like tripeptide linked to elaidic acid. Biochem. Pharmacol. 67, 2013–2022. 10.1016/j.bcp.2004.01.028 - DOI - PubMed
    1. Choi Y. L., Park E. J., Kim E., Na D. H., Shin Y. (2014). Dermal stability and in vitro skin permeation of collagen pentapeptides (KTTKS and palmitoyl-KTTKS). Biomol. Ther. 22, 321–327. 10.4062/biomolther.2014.053 - DOI - PMC - PubMed

LinkOut - more resources