Review
doi: 10.1016/s0891-5849(87)80039-4.
The electroanalytical approach to lipid peroxide determinations
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- PMID: 3319796
- DOI: 10.1016/s0891-5849(87)80039-4
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Review
The electroanalytical approach to lipid peroxide determinations
Free Radic Biol Med.
1987.
Abstract
An electroanalytical method for the determination of lipid peroxides in physiological material is described. The technique is based on electrochemical detection for HPLC as the means for enhancing sensitivity. Samples containing organic peroxides, including lipid peroxides, can be analyzed directly using a modified polarographic detector (Lloyd, J.B.F.; Optimization of the operational parameters of the supported mercury drop electrode detector in high performance liquid chromatography. Anal. Chim. Acta 154:121-131; 1983.) for reversed phase HPLC determinations. Detection limits for fatty acid hydroperoxides were found to be in the low nanogram range.
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