Safety questions for AAV gene therapy
- PMID: 33199877
- DOI: 10.1038/s41587-020-00756-9
Safety questions for AAV gene therapy
Comment on
-
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells.Nat Biotechnol. 2021 Jan;39(1):47-55. doi: 10.1038/s41587-020-0741-7. Epub 2020 Nov 16. Nat Biotechnol. 2021. PMID: 33199875 Free PMC article.
References
-
- Nguyen, G. N. Nat. Biotechnol. https://doi.org/10.1038/s41587-020-0741-7 (2020).
-
- Chandler, R. J., Sands, M. S. & Venditti, C. P. Hum. Gene Ther. 28, 314–322 (2017). - DOI
-
- Donsante, A. et al. Science 317, 477 (2007). - DOI
-
- Chandler, R. J. et al. J. Clin. Invest. 125, 870–880 (2015). - DOI
-
- Wang, P. R. et al. Proc. Natl. Acad. Sci. USA 109, 11264–11269 (2012). - DOI
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
