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. 2020 Dec:60:526-530.
doi: 10.1016/j.amsu.2020.11.030. Epub 2020 Nov 12.

Large vessel thrombosis in patient with COVID-19, a case series

Aram Baram  1 , Fahmi H Kakamad  1   2   3 , Hadi M Abdullah  4 , Dana H Mohammed-Saeed  1   2   5 , Dahat A Hussein  2   3 , Shvan H Mohammed  3 , Binar B Abdulrahman  6   7   8 , Aram J Mirza  5   6 , Berwn A Abdulla  2   3 , Hawbash M Rahim  2   3 , Mohammed J Rashid  4 , Farhad F Mohammed-Al  4 , Yad N Othman  4 , Abdulwahid M Salih  1   2
Affiliations

Large vessel thrombosis in patient with COVID-19, a case series

Aram Baram et al. Ann Med Surg (Lond). 2020 Dec.

Abstract

Introduction: Involvement of the large vessels is rarely reported and poorly understood in cases of Corona virus disease-19 (COVID-19). The aim of this study is to present a series of cases with large vessel thrombosis (LVT).

Methods: This is a multicenter prospective case series study. The participants were consecutive in order. All the patients were diagnosed as cases of COVID-19 with documented LVT were included in the study. Large vessels were defined as any vessel equal or larger than popliteal artery. The mean duration of follow up was 4 months.

Results: The study included 22 cases, 19 (86.4%) cases were male, 3 (13.6%) patients were females. The age ranged from 23 to 76 with a mean of 48.4 years. Four (18.2%) cases had pulmonary embolism confirmed by IV contrast enhanced chest CT scan. All of the cases showed pulmonary parenchymal ground glass opacities (GGO) and high D-Dimers (ranging from 1267 to 6038 ng/ml with a mean of 3601 ng/ml).

Conclusion: COVID-19 is a hidden risk factor of LVT that may endanger the patient's life and lead to major amputation. Despite therapeutic anticoagulants still all COVID-19 patients are at risk for LVT, a high index of suspicion should be created and with minimal symptoms surgical consultation should be obtained.

Keywords: COVID-19; Ischemia; SARS-CoV-2; Thrombosis.

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Figures

Fig. 1
Fig. 1
Computed tomography scan (axial view) with IV contrast showing bilateral pulmonary embolism.
Fig. 2
Fig. 2
Computed tomography scan (axial view) showing diffuse bilateral patches of ground glass opacities.
See this image and copyright information in PMC

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