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Published Erratum
. 2021 Jun;87(6):879-880.
doi: 10.1007/s00280-020-04194-x.

Correction to: Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega‑3 polyunsaturated fatty acid eicosapentaenoic acid

Milene Volpato  1 , Nicola Ingram  2 , Sarah L Perry  2 , Jade Spencer  3 , Amanda D Race  3 , Catriona Marshall  2 , John M Hutchinson  2 , Anna Nicolaou  4   5 , Paul M Loadman  3 , P Louise Coletta  2 , Mark A Hull  2
Affiliations
Published Erratum

Correction to: Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega‑3 polyunsaturated fatty acid eicosapentaenoic acid

Milene Volpato et al. Cancer Chemother Pharmacol. 2021 Jun.
No abstract available

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Figures

Fig. 2
Fig. 2
COX expression mediates EPA sensitivity of CRC cells in vitro. a MTT cell viability assay curves for the effect of EPA on MC38 (closed circles) and MC38r mouse CRC cells (open circles). Data represent the mean ± SEM % growth compared to untreated control cells for three independent replicates for each mouse CRC cell line. b Western blot analysis of COX isoform protein expression in MC38 and MC38r mouse CRC cells. c PGE2 levels in medium conditioned by MC38 and MC38r cells for 24 h. Data compared with Student’s t test. d Western blot analysis of COX isoform protein expression in CT26 and COXlow-CT26 mouse CRC cells. e PGE2 levels in medium conditioned by CT26 and COXlow-CT26 mouse CRC cells for 24 h. Data compared with Student’s t test. f MTT cell viability assay curves for the effect of EPA on CT26 (closed circles) and COXlow-CT26 mouse CRC cells (open circles). Data represent the mean ± SEM % growth compared to untreated control cells for three independent replicates for each mouse CRC cell line. Two-way ANOVA confirmed a significant increase in EPA sensitivity of COXlow-CT26 cells compared with CT26 mouse CRC cells (p = 0.03)
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