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. 2021 Jan;34(1):e14551.
doi: 10.1111/dth.14551. Epub 2020 Nov 25.

Possible association between IgA vasculitis and COVID-19

Sunmeet Sandhu  1 , Satish Chand  1 , Anuj Bhatnagar  1 , Rajeshwari Dabas  1 , Showkat Bhat  1 , Harish Kumar  2 , Prashant Kumar Dixit  2
Affiliations

Possible association between IgA vasculitis and COVID-19

Sunmeet Sandhu et al. Dermatol Ther. 2021 Jan.
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
A,B, Multiple, discrete to confluent purpura seen over forearm, arm, and thighs. C,D, Edema over wrist, hand, and ankle also noted
FIGURE 2
FIGURE 2
A, Histopathology was suggestive of leukocytoclastic vasculitis with features of plump endothelial cells (black arrow) with perivascular mixed inflammatory infiltrate comprising of neutrophils and lymphocytes and extravasation of RBCs in upper dermis (black star). B, Few capillaries show fibrinoid change of the vessel wall (blue arrow). (A: H&E, ×20 and B: H&E, ×80)
FIGURE 3
FIGURE 3
Kidney biopsy showed mesangial granular deposits of IgA
See this image and copyright information in PMC

References

    1. Galván Casas C, Català A, Carretero Hernández G, et al. Classification of the cutaneous manifestations of COVID‐19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020;183:71‐77. - PMC - PubMed
    1. Allez M, Denis B, Bouaziz J‐D, et al. Covid‐19 related IgA vasculitis. Arthritis Rheumatol (Hoboken, NJ). 2020;72:1952‐1953. - PMC - PubMed
    1. Suso AS, Mon C, Alonso IO, et al. IgA vasculitis with nephritis (Henoch‐Schönlein purpura) in a COVID‐19 patient. Kidney Int Rep. 2020;5:2074‐2078. 10.1016/j.ekir.2020.08.016. - DOI - PMC - PubMed
    1. Wang JJ, Xu Y, Liu FF, et al. Association of the infectious triggers with childhood Henoch–Schonlein purpura in Anhui province, China. J Infect Public Health. 2020;13:110‐117. - PubMed
    1. Varga Z, Flammer AJ, Steiger P, et al. Endothelial cell infection and endotheliitis in COVID‐19. Lancet. 2020;395(10234):1417‐1418. - PMC - PubMed

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