Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Dec;59(12):1472-1479.
doi: 10.1007/s00120-020-01385-5.

[Antibiotic stewardship (ABS)-strategies for urologists in private practice and hospitals]

[Article in German]
U Lichtinger  1 , V Greifenberg  2 , A Gessner  3
Affiliations
Review

[Antibiotic stewardship (ABS)-strategies for urologists in private practice and hospitals]

[Article in German]
U Lichtinger et al. Urologe A. 2020 Dec.

Abstract
in English, German

Antibiotics are effective and safe drugs which have saved millions of lives since their inception. The World Health organization (WHO) has identified increasing antibiotic resistance worldwide as one of the greatest health problems of our time. The most common indications for antibiotic therapy include urinary tract infections, but according to current data, a very high percentage of these are not treated in accordance with guidelines. To prevent the continuous selection of resistant bacteria, and undesirable or even dangerous side effects such as by avoiding damage to the patient's microbiome, strategies through antibiotic stewardship (ABS) are urgently needed. Especially for urologists in outpatient care, this requires new, innovative and sustainable training concepts that keep knowledge continuously up-to-date and support appropriate antibiotic prescriptions.

Antibiotika sind wirksame und sichere Arzneimittel und haben seit ihrer Einführung Millionen von Menschenleben gerettet. Die Weltgesundheitsorganisation (WHO) hat die weltweit zunehmenden Antibiotikaresistenzen als eines der größten Gesundheitsprobleme der Gegenwart identifiziert. Zu den häufigsten Indikationen für eine Antibiotikatherapie gehören Harnwegsinfektionen, bei denen nach aktuellen Erfassungen in einem sehr hohen Prozentsatz allerdings nicht leitliniengerecht behandelt wird. Um die fortlaufende Selektion von resistenten Bakterien, und unerwünschte oder sogar gefährliche Nebenwirkungen wie z. B. durch Schädigungen des Mikrobioms der Patienten zu vermeiden, sind dringend Strategien zur Verbesserung der Antibiotikatherapie durch „antibiotic stewardship“ (ABS) erforderlich. Insbesondere für Urologen in der ambulanten Patientenversorgung bedarf es hierfür neuer, innovativer und nachhaltiger Schulungskonzepte, die Wissen kontinuierlich aktuell halten und sachgerechte Antibiotikaverschreibungen nachhaltig unterstützen.

Keywords: Antibiotic resistance, microbial; Diagnostic stewardship; Microbiome; Reduction of antibiotics; Urinary tract infection.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Klein EY, Van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin SA, Goossens H, Laxminarayan R. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proc Natl Acad Sci U S A. 2018;115:3463. doi: 10.1073/pnas.1717295115. - DOI - PMC - PubMed
    1. Gagyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial. BMJ. 2015;351:6544. doi: 10.1136/bmj.h6544. - DOI - PMC - PubMed
    1. Wagenlehner FM, Abramov-Sommariva D, Höller M, Steindl H, Naber KG. Non-antibiotic herbal therapy (BNO 1045) versus antibiotic therapy (Fosfomycin Trometamol) for the treatment of acute lower uncomplicated urinary tract infections in women: a double-blind, parallel-group, randomized, Multicentre, non-inferiority phase III trial. Urol Int. 2018;101:327. doi: 10.1159/000493368. - DOI - PMC - PubMed
    1. Shallcross L, Rockenschaub P, Blackburn R, Nazareth I, Freemantle N, Hayward A. Antibiotic prescribing for lower UTI in elderly patients in primary care and risk of bloodstream infection: a cohort study using electronic health records in England. PLoS Med. 2020;17(9):e1003336. doi: 10.1371/journal.pmed.1003336. - DOI - PMC - PubMed
    1. McKenna M. The antibiotic gamble. Nature. 2020;584:338. doi: 10.1038/d41586-020-02418-x. - DOI - PubMed

Substances

LinkOut - more resources