Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Mar;31(3):245-246.
doi: 10.1038/s41422-020-00440-2.

Gephyrin: a scaffold that builds a phase at the inhibitory postsynapses

Affiliations
Comment

Gephyrin: a scaffold that builds a phase at the inhibitory postsynapses

Christian Hoffmann et al. Cell Res. 2021 Mar.

Erratum in

No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1. Scheme of gephyrin-mediated liquid condensation at the inhibitory postsynapse.
LLPS (yellow) is induced by the interaction of gephyrin (blue) with the subunits of glycine and GABAA receptors (GlyR and GABAAR, respectively; green). Gephyrin consists of G-domain (PDBID: 1IHC) and E-domain (PDBID: 2FU3) linked by a flexible C-domain. Scheme was generated with BioRender.

Comment on

References

    1. Tao CL, et al. J. Neurosci. 2018;38:1493–1510. doi: 10.1523/JNEUROSCI.1548-17.2017. - DOI - PMC - PubMed
    1. Zeng M, et al. Cell. 2016;166:1163–1175. doi: 10.1016/j.cell.2016.07.008. - DOI - PMC - PubMed
    1. Zeng M, et al. Cell. 2018;174:1172–1187. doi: 10.1016/j.cell.2018.06.047. - DOI - PubMed
    1. Banani SF, et al. Nat. Rev. Mol. Cell Biol. 2017;18:285–298. doi: 10.1038/nrm.2017.7. - DOI - PMC - PubMed
    1. Bai, G. et al. Cell Res. 10.1038/s41422-020-00433-1 (2020).