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. 2020 Nov 10;18(11):e06280.
doi: 10.2903/j.efsa.2020.6280. eCollection 2020 Nov.

Safety and efficacy of Bacillus subtilis PB6 (Bacillus velezensis ATCC PTA-6737) as a feed additive for chickens for fattening, chickens reared for laying, minor poultry species (except for laying purposes), ornamental, sporting and game birds

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP); Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Maryline Kouba, Mojca Fašmon Durjava, Marta López-Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Pier Sandro Cocconcelli, Boet Glandorf, Lieve Herman, Miguel Prieto Maradona, Maria Saarela, Rosella Brozzi, Jaume Galobart, Lucilla Gregoretti, Gloria López-Gálvez, Maria Vittoria Vettori, Matteo Lorenzo Innocenti, Konstantinos Sofianidis

Safety and efficacy of Bacillus subtilis PB6 (Bacillus velezensis ATCC PTA-6737) as a feed additive for chickens for fattening, chickens reared for laying, minor poultry species (except for laying purposes), ornamental, sporting and game birds

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al. EFSA J. .

Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the renewal of the authorisation of Bacillus subtilis PB6, the extension of use to ornamental, sporting and game birds and a modification on the concentration of the said additive. The product under assessment is based on viable spores of a strain originally identified as Bacillus subtilis. During the course of the current assessment, the active agent has been redesignated as Bacillus velezensis ATCC PTA-6737. The bacterial species B. velezensis is considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The identity of the active agent is established and the compliance with the other qualifications confirmed. Therefore, B. velezensis ATCC PTA-6737 is presumed safe for the target species, consumers of products derived from animals fed the additive and the environment. The additive is not a dermal/eye irritant or a skin sensitiser. Exposure via inhalation is unlikely. In the previous assessments performed by the FEEDAP Panel, the additive showed to be efficacious as a zootechnical additive in feedingstuffs for chickens for fattening and chickens reared for laying at the level of 1 × 107 CFU/kg. Considering that efficacy at the same level has been shown, this conclusion is extrapolated to ornamental, sporting and gaming birds.

Keywords: Bacillus velezensis; QPS; chickens; efficacy; gut flora stabiliser; poultry; zootechnical additive.

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References

    1. EFSA (European Food Safety Authority), 2007. Opinion of the Scientific Committee on a request from EFSA on the introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA. EFSA Journal 2007;5(12):587, 16 pp. 10.2903/j.efsa.2007.587 - DOI
    1. EFSA NDA Panel (Panel on Dietetic Products, Nutrition and Allergies), 2009. Scientific Opinion on the substantiation of health claims related to non‐characterised microorganisms pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal 2009;7(9):1247, 64 pp. 10.2903/j.efsa.2009.1247 - DOI
    1. EFSA FEEDAP Panel (Panel on Additives and Products or Substances used in Animal Feed), 2009. Scientific Opinion on the safety and efficacy of Bacillus subtilis PB6 (Bacillus subtilis) as a feed additive for chickens for fattening. EFSA Journal 2009;7(9):1314, 14 pp. 10.2903/j.efsa.2009.1314 - DOI
    1. EFSA FEEDAP Panel (Panel on Additives and Products or Substances used in Animal Feed), 2010. Scientific Opinion on the compatibility of Bacillus subtilis PB6 (Bacillus subtilis) with coccidiostats in chickens for fattening. EFSA Journal 2010;8(10):1836, 6 pp. 10.2903/j.efsa.2010.1836 - DOI
    1. EFSA FEEDAP Panel (Panel on Additives and Products or Substances used in Animal Feed), 2011. Scientific Opinion on the safety and efficacy of Bacillus subtilis PB6 for chickens reared for laying, ducks for fattening, quails, pheasants, partridges, guinea fowl, pigeons, geese for fattening and ostriches. EFSA Journal 2011;9(3):2114, 8 pp. 10.2903/j.efsa.2011.2114 - DOI