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Comment
. 2021 Jun;73(6):2617-2618.
doi: 10.1002/hep.31640.

Letter to the Editor: Should Growth Pattern of Hepatocellular Carcinoma Be Constant and Homogenous?

Affiliations
Comment

Letter to the Editor: Should Growth Pattern of Hepatocellular Carcinoma Be Constant and Homogenous?

Haofan Wang et al. Hepatology. 2021 Jun.
No abstract available

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Comment in

  • REPLY.
    Rich NE, Marrero JA, Singal AG. Rich NE, et al. Hepatology. 2021 Jun;73(6):2618-2619. doi: 10.1002/hep.31638. Epub 2021 May 17. Hepatology. 2021. PMID: 33205463 Free PMC article. No abstract available.

Comment on

References

    1. Rich NE, John BV, Parikh ND, Rowe I, Mehta N, Khatri G, et al. Hepatocellular carcinoma demonstrates heterogeneous growth patterns in a multi-center cohort of patients with cirrhosis. Hepatology 2020;72:1654-1665.
    1. Schwartz M. A biomathematical approach to clinical tumor growth. Cancer 1961;14:1272-1294.
    1. Kareva I, Karev G. Modeling Evolution of Heterogeneous Populations: Theory and Applications. Cambridge, MA: Academic Press; 2019.
    1. Heimbach JK, Kulik LM, Finn RS, Sirlin CB, Abecassis MM, Roberts LR, et al. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology 2018;67:358-380.
    1. Gao Q, Wang ZC, Duan M, Lin YH, Zhou XY, Worthley DL, et al. Cell culture system for analysis of genetic heterogeneity within hepatocellular carcinomas and response to pharmacologic agents. Gastroenterology 2017;152:232-242.