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Comment
. 2021 Jun;12(6):1118-1119.
doi: 10.1111/jdi.13442. Epub 2020 Nov 18.

Relationship between soluble transferrin receptor and type 2 diabetes mellitus: A meta-analysis

José Cándido Fernández-Cao  1
Affiliations
Comment

Relationship between soluble transferrin receptor and type 2 diabetes mellitus: A meta-analysis

José Cándido Fernández-Cao. J Diabetes Investig. 2021 Jun.

Abstract

Obesity may play a role in the association between sTfR and T2DM. Analysis of the review carried out by Liu et al. titled "Iron metabolism and type 2 diabetes mellitus: A meta-analysis and systematic review".

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Forest plot of the pooled effect size of the highest versus lowest soluble transferrin receptor for type 2 diabetes mellitus according to obesity (non‐obese, mixed and obese participants). Squares represent odds ratios for each study, and the size of the square is the study‐specific statistical weight. Horizontal lines show the 95% confidence interval (CI) of each study. The diamond represents the odds ratio estimate with corresponding 95% CI. OR, odds ratio.
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References

    1. Liu J, Li Q, Yang Y, et al. Iron metabolism and type 2 diabetes mellitus: a meta‐analysis and systematic review. J Diabetes Investig 2020; 11: 946–955. - PMC - PubMed
    1. Fernández‐Cao JC, Arija V, Aranda N, et al. Soluble transferrin receptor and risk of type 2 diabetes in the obese and nonobese. Eur J Clin Invest 2017; 47: 221–230. - PubMed
    1. Rajpathak SN, Wylie‐Rosett J, Gunter MJ, et al. Biomarkers of body iron stores and risk of developing type 2 diabetes. Diabetes, Obes Metab 2009; 11: 472–479. - PMC - PubMed
    1. Arija V, Fernández‐Cao JC, Basora J, et al. Excess body iron and the risk of type 2 diabetes mellitus: a nested case–control in the PREDIMED (PREvention with MEDiterranean Diet) study. Br J Nutr 2014; 112: 1896–1904. - PubMed