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. 2020 Dec;9(1):2497-2500.
doi: 10.1080/22221751.2020.1851146.

Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

Gilman Kit-Hang Siu  1 , Lam-Kwong Lee  1 , Kenneth Siu-Sing Leung  2 , Jake Siu-Lun Leung  1 , Timothy Ting-Leung Ng  1 , Chloe Toi-Mei Chan  1 , Kingsley King-Gee Tam  2 , Hiu-Yin Lao  1 , Alan Ka-Lun Wu  3 , Miranda Chong-Yee Yau  3 , Yvette Wai-Man Lai  3 , Kitty Sau-Chun Fung  4 , Sandy Ka-Yee Chau  4 , Barry Kin-Chung Wong  4 , Wing-Kin To  5 , Kristine Luk  5 , Alex Yat-Man Ho  5 , Tak-Lun Que  6 , Kam-Tong Yip  6 , Wing Cheong Yam  2 , David Ho-Keung Shum  7 , Shea Ping Yip  1
Affiliations

Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

Gilman Kit-Hang Siu et al. Emerg Microbes Infect. 2020 Dec.
No abstract available

Keywords: COVID-19; Phylogeny; SARS-CoV-2; outbreak; whole genome sequencing.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Phylogenetic tree constructed by PhyML using maximum likelihood with bootstrap value set at 1000×. The tree was rooted on the earliest published genome (accession no.: NC_045512.2). Each genomic sequence consisted of 29,782 bp. A total of 360 variable sites were identified by multiple alignment and were used for phylogenetic tree construction. Specimens were labelled by the CHP case number followed by the diagnostic date (YYYYMMDD). Asymptomatic patients were bolded and imported cases were labelled by the departing countries. The letters on the right of the figure are the GISAID phylogenetic clades. Branch lengths were measured in number of substitutions per site. The bar with 0.00020 means that there are approximately 6 substitutions (0.0002 × 29,903 bp) difference when two strains were located at the opposite end of a bar of this length. Branches were highlighted as follow: Orange for cases from January to February (genomes generated in our previous work [1]); Green for cases from March to April; Blue for cases from July to August; and Red for recent cases in September to October (genomes generated in the present study). Locally acquired cases recorded in October were circled by Cyan box.
See this image and copyright information in PMC

References

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    1. To KK, Chan WM, Ip JD, et al. . Unique SARS-CoV-2 clusters causing a large COVID-19 outbreak in Hong Kong. Clin Infect Dis. 2020 Aug 5. doi:10.1093/cid/ciaa1119. PubMed PMID: 32756996; PubMed Central PMCID: PMCPMC7454385. - DOI - PMC - PubMed
    1. Centre_for_Health_Protection. Latest situation of cases of COVID-19 . (as of 11 October 2020). 2020 [cited 2020 October 11]. Available from: https://www.chp.gov.hk/files/pdf/local_situation_covid19_en.pdf
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