Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May 1;56(5):313-319.
doi: 10.1097/RLI.0000000000000743.

Diagnostic Confidence and Feasibility of a Deep Learning Accelerated HASTE Sequence of the Abdomen in a Single Breath-Hold

Judith Herrmann  1 , Sebastian Gassenmaier  1 , Dominik Nickel  2 , Simon Arberet  3 , Saif Afat  1 , Andreas Lingg  1 , Matthias Kündel  1 , Ahmed E Othman  1
Affiliations

Diagnostic Confidence and Feasibility of a Deep Learning Accelerated HASTE Sequence of the Abdomen in a Single Breath-Hold

Judith Herrmann et al. Invest Radiol. .

Abstract

Objective: The aim of this study was to evaluate the feasibility of a single breath-hold fast half-Fourier single-shot turbo spin echo (HASTE) sequence using a deep learning reconstruction (HASTEDL) for T2-weighted magnetic resonance imaging of the abdomen as compared with 2 standard T2-weighted imaging sequences (HASTE and BLADE).

Materials and methods: Sixty-six patients who underwent 1.5-T liver magnetic resonance imaging were included in this monocentric, retrospective study. The following T2-weighted sequences in axial orientation and using spectral fat suppression were compared: a conventional respiratory-triggered BLADE sequence (time of acquisition [TA] = 4:00 minutes), a conventional multiple breath-hold HASTE sequence (HASTES) (TA = 1:30 minutes), as well as a single breath-hold HASTE with deep learning reconstruction (HASTEDL) (TA = 0:16 minutes). Two radiologists assessed the 3 sequences regarding overall image quality, noise, sharpness, diagnostic confidence, and lesion detectability as well as lesion characterization using a Likert scale ranging from 1 to 4 with 4 being the best. Comparative analyses were conducted to assess the differences between the 3 sequences.

Results: HASTEDL was successfully acquired in all patients. Overall image quality for HASTEDL was rated as good (median, 3; interquartile range, 3-4) and was significantly superior to HASTEs (P < 0.001) and inferior to BLADE (P = 0.001). Noise, sharpness, and artifacts for HASTEDL reached similar levels to BLADE (P ≤ 0.176) and were significantly superior to HASTEs (P < 0.001). Diagnostic confidence for HASTEDL was rated excellent by both readers and significantly superior to HASTEs (P < 0.001) and inferior to BLADE (P = 0.044). Lesion detectability and lesion characterization for HASTEDL reached similar levels to those of BLADE (P ≤ 0.523) and were significantly superior to HASTEs (P < 0.001). Concerning the number of detected lesions and the measured diameter of the largest lesion, no significant differences were found comparing BLADE, HASTES, and HASTEDL (P ≤ 0.912).

Conclusions: The single breath-hold HASTEDL is feasible and yields comparable image quality and diagnostic confidence to standard T2-weighted TSE BLADE and may therefore allow for a remarkable time saving in abdominal imaging.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Michaely HJ, Morelli JN, Budjan J, et al. CAIPIRINHA-Dixon-TWIST (CDT)-volume-interpolated breath-hold examination (VIBE): a new technique for fast time-resolved dynamic 3-dimensional imaging of the abdomen with high spatial resolution. Invest Radiol . 2013;48:590–597.
    1. Brodsky EK, Bultman EM, Johnson KM, et al. High-spatial and high-temporal resolution dynamic contrast-enhanced perfusion imaging of the liver with time-resolved three-dimensional radial MRI. Magn Reson Med . 2014;71:934–941.
    1. Fowler KJ, Brown JJ, Narra VR. Magnetic resonance imaging of focal liver lesions: approach to imaging diagnosis. Hepatology . 2011;54:2227–2237.
    1. Bashir MR, Castelli P, Davenport MS, et al. Respiratory motion artifact affecting hepatic arterial phase MR imaging with gadoxetate disodium is more common in patients with a prior episode of arterial phase motion associated with gadoxetate disodium. Radiology . 2015;274:141–148.
    1. Park YS, Lee J, Kim JW, et al. Second shot arterial phase to overcome degraded hepatic arterial phase in liver MR imaging. Eur Radiol . 2019;29:2821–2829.

LinkOut - more resources