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Review
. 2020 Dec;9(6):580-588.
doi: 10.1097/APO.0000000000000338.

Lamellar Keratoplasty for Advanced Keratoconus

Moushmi Patil  1 , Jodhbir S Mehta  1   2   3
Affiliations
Free article
Review

Lamellar Keratoplasty for Advanced Keratoconus

Moushmi Patil et al. Asia Pac J Ophthalmol (Phila). 2020 Dec.
Free article

Abstract

Ectatic corneal diseases are a group of disorders resulting in progressive corneal steepening and thinning. Keratoconus, keratoglobus, pellucid marginal degeneration, post-keratorefractive ectasia, and corneal graft ectasia are the types of corneal ectasia. Early diagnosis with appropriate diagnostic tools can help prevent progression, eliminating the need for corneal transplantation. Lamellar or full thickness corneal transplantation are the treatment options for advanced diseases. Although the visual outcomes of penetrating keratoplasty are comparable to anterior lamellar keratoplasty (ALK) especially in keratoconus, ALK is the preferred treatment of choice considering benefits including reduced graft rejection, less long-term complications, and better graft survival. This article reviews the various surgical techniques in ALK with its clinical outcomes in advanced keratoconus.

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References

    1. Ambrósio R Jr, Dawson DG, Salomão M, et al. Corneal ectasia after LASIK despite low preoperative risk: tomographic and biomechanical findings in the unoperated, stable, fellow eye. J Refract Surg 2010; 26:906–911.
    1. Patel SV, Tester R, Soong HK, et al. Recurrent ectasia after penetrating keratoplasty for keratoconus. Invest Ophthalmol Vis Sc May 2005; 46:4948.
    1. Chang HY, Chodosh J. The genetics of keratoconus. Semin Ophthalmol 2013; 28:275–280.
    1. Wallang BS, Das S. Keratoglobus. Eye (Lond) 2013; 27:1004–1012.
    1. Krachmer JH, Feder RS, Belin MW. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol 1984; 28:293–322.