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. 2021 Jan;48(1):49-55.
doi: 10.1111/1346-8138.15629. Epub 2020 Nov 19.

Neurogenic rosacea in Korea

Hye One Kim  1 , Seok Young Kang  1 , Ko Eun Kim  2 , So Yun Cho  3 , Kwang Ho Kim  4 , Il-Hwan Kim  2
Affiliations

Neurogenic rosacea in Korea

Hye One Kim et al. J Dermatol. 2021 Jan.

Abstract

Rosacea with severe neurological symptoms such as burning and stinging is often not treated effectively by conventional therapies. The aim of this study was to investigate the clinical characteristics of Korean rosacea patients with prominent neurological symptoms. The demographic features, medical history, clinical manifestations and treatment modalities of 17 neurogenic rosacea patients who had prominent neurological symptoms and 106 erythematotelangiectatic rosacea (ETR) patients as a control group were investigated. All 17 neurogenic rosacea patients had severe persistent erythema with burning/stinging sensation limited to both cheeks. Among these patients, 94.1% were female (16/17). Heat stimuli (58.8%, 10/17) and stress (52.9%, 9/17) were major aggravating factors. Fourteen of 17 patients (82.3%) improved after receiving anticonvulsants and antidepressants. In conclusion, rosacea patients with severe neurological symptoms show distinct clinical manifestations and should be classified separately, and a different therapeutic approach is necessary for them.

Keywords: neurogenic rosacea; neurological manifestations; rosacea; skin manifestation; therapy.

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References

REFERENCES

    1. Two AM, Wu W, Gallo RL, Hata TR. Rosacea: part I. Introduction, categorization, histology, pathogenesis, and risk factors. J Am Acad Dermatol 2015; 72(5): 749-758.
    1. Gallo RL, Granstein RD, Kang S et al. Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee. J Am Acad Dermatol 2018; 78(1): 148-155.
    1. Wilkin J, Dahl M, Detmar M et al. Standard grading system for rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosacea. J Am Acad Dermatol 2004; 50(6): 907-912.
    1. Zhao YE, Wu LP, Peng Y et al. Retrospective analysis of the association between Demodex infestation and rosacea. Arch Dermatol 2010; 146(8): 896-902.
    1. Lacey N, Delaney S, Kavanagh K et al. Mite-related bacterial antigens stimulate inflammatory cells in rosacea. Br J Dermatol 2007; 157(3): 474-481.

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