[Progression of pathogenesis, diagnosis and treatment of diversion colitis]
- PMID: 33212566
- DOI: 10.3760/cma.j.cn.441530-20191031-00468
[Progression of pathogenesis, diagnosis and treatment of diversion colitis]
Abstract
Diversion colitis (DC) is a common non-specific inflammation of the malfunctioning bowel segment after diversion of feces. Although most patients develop DC during stoma, there are no obvious clinical symptoms, and a small number of patients show abdominal pain, mucus discharge and hematochezia. The erythema, diffuse particles and vascular texture blur are the most prominent endoscopic manifestations, and the lymphatic follicular hyperplasia is the most prominent pathological manifestations.Reconstruction of intestinal continuity is the best way to cure recanted colitis. In this review, we summarize and review the mechanism of occurrence, clinical features, diagnosis and treatment of DC, which will be helpful for the effective control and prevention of DC.
改道性结肠炎(DC)是粪便流改道后功能失调肠段常见的非特异性炎性反应,发病机制尚不清楚,可能与肠道菌群紊乱、短链脂肪酸的缺乏及免疫炎性反应因素等有关。虽然绝大多数患者造口期间并发DC,但往往无明显临床症状,少部分患者表现为腹痛、黏液排出及便血等症状。内镜表现以肠道黏膜红斑、弥散性颗粒及血管纹理模糊最显著,病理表现以淋巴滤泡增生最显著,可用于DC的诊断及预后评估。DC应依据病情的不同程度给予差异化治疗。无症状或无手术指征的患者建议行随访和保守治疗,包括利用短链脂肪酸、5-氨基水杨酸、类固醇、纤维素溶液等药物灌肠。有明显症状、结肠炎或腹泻病史的患者,建议尽早行外科闭合吻合口术,重建肠道连续性。.
Keywords: Diagnosis; Diversion colitis; Enterostomy; Mechanism of occurrence; Treatment.
Similar articles
-
A prospective evaluation of diversion colitis.Am Surg. 1991 Jan;57(1):46-9. Am Surg. 1991. PMID: 1796797
-
Pathophysiology, clinical presentation and management of diversion colitis: a review of current literature.Int J Surg. 2014 Oct;12(10):1088-92. doi: 10.1016/j.ijsu.2014.08.350. Epub 2014 Aug 20. Int J Surg. 2014. PMID: 25150021 Review.
-
Diversion colitis and pouchitis: A mini-review.World J Gastroenterol. 2018 Apr 28;24(16):1734-1747. doi: 10.3748/wjg.v24.i16.1734. World J Gastroenterol. 2018. PMID: 29713128 Free PMC article. Review.
-
Diversion colitis: histological features in the colon and rectum after defunctioning colostomy.Gut. 1991 Sep;32(9):1020-3. doi: 10.1136/gut.32.9.1020. Gut. 1991. PMID: 1916483 Free PMC article.
-
[Diversion colitis].Rev Esp Enferm Dig. 1994 Dec;86(6):898-900. Rev Esp Enferm Dig. 1994. PMID: 7873265 Review. Spanish. No abstract available.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources