Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Nov 17;10(11):964.
doi: 10.3390/diagnostics10110964.

Complications of Endoscopic Ultrasound-Guided Fine Needle Aspiration: A Narrative Review

Masafumi Mizuide  1 , Shomei Ryozawa  1 , Akashi Fujita  1 , Tomoya Ogawa  1 , Hiromune Katsuda  1 , Masahiro Suzuki  1 , Tatsuya Noguchi  1 , Yuki Tanisaka  1
Affiliations
Review

Complications of Endoscopic Ultrasound-Guided Fine Needle Aspiration: A Narrative Review

Masafumi Mizuide et al. Diagnostics (Basel). .

Abstract

Considerable progress has been made recently in the use of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) to diagnose intra-luminal gastrointestinal lesions and extra-luminal lesions near the gastrointestinal tract. Numerous reports have indicated that EUS-FNA has high diagnostic performance and safety, which has led to the routine use of EUS-FNA and an increasing number of cases. Thus, while EUS-FNA has a low rate of complications, endoscopists may encounter these complications as the number of cases increases. Infrequent reports have also described life-threatening complications. Therefore, endoscopists should possess a comprehensive understanding of the complications of EUS-FNA, which include hemorrhage, perforation, infection, and acute pancreatitis, as well as their management. This review examines the available evidence regarding the complications associated with EUS-FNA, and the findings will be useful for ensuring that endoscopists perform EUS-FNA safely and appropriately.

Keywords: bleeding; complications; endoscopic ultrasound-guided fine-needle aspiration; infection; morbidity; mortality; needle tract seeding; pancreatitis; perforation.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Vilmann P., Jacobsen G.K., Henriksen F.W., Hancke S. Endoscopic ultrasonography with guided fine needle aspiration biopsy in pancreatic disease. Gastrointest. Endosc. 1992;38:172–173. doi: 10.1016/S0016-5107(92)70385-X. - DOI - PubMed
    1. Mekky M.A., Yamao K., Sawaki A., Mizuno N., Hara K., Nafeh M.A., Osman A.M., Koshikawa T., Yatabe Y., Bhatia V. Diagnostic utility of EUS-guided FNA in patients with gastric submucosal tumors. Gastrointest. Endosc. 2010;71:913–919. doi: 10.1016/j.gie.2009.11.044. - DOI - PubMed
    1. Zhang L., Sanagapalli S., Stoita A. Challenges in diagnosis of pancreatic cancer. World J. Gastroenterol. 2018;21:2047–2060. doi: 10.3748/wjg.v24.i19.2047. - DOI - PMC - PubMed
    1. Iwashita T., Yasuda I., Tsurumi H., Goto N., Nakashima M., Doi S., Hirose Y., Takami T., Moriwaki H. Endoscopic ultrasound-guided fine needle aspiration biopsy for splenic tumor: A case series. Endoscopy. 2009;41:179–182. doi: 10.1055/s-0028-1119474. - DOI - PubMed
    1. Martin-Cardona A., Fernandez-Esparrach G., Subtil J.C., Iglesias-Garcia J., Garcia-Guix M., Barturen Barroso A., Gimeno-Garcia A.Z., Esteban J.M., Pardo Balteiro A., Velasco-Guardado A., et al. EUS-guided tissue acquisition in the study of the adrenal glands: Results of a nationwide multicenter study. PLoS ONE. 2019;6:e0216658. doi: 10.1371/journal.pone.0216658. - DOI - PMC - PubMed

LinkOut - more resources